Nombre de documents archivés : 44.
Centre INRS-Institut Armand Frappier
Asaba, Clinton Njinju; Bitazar, Razieh; Labonté, Patrick
ORCID: https://orcid.org/0000-0001-7262-3125 et Bukong, Terence Ndonyi
ORCID: https://orcid.org/0000-0003-3898-0617
(2025).
Bronchoalveolar lavage single-cell transcriptomics reveals immune dysregulations driving COVID-19 severity
PLoS One
, vol. 20
, nº 2.
pp. 1-26.
DOI: 10.1371/journal.pone.0309880.
Khabir, Marwa; Blanchet, Matthieu; Angelo, Léna; Loucif, Hamza; van Grevenynghe, Julien
ORCID: https://orcid.org/0000-0002-2952-4081; Bukong, Terence Ndonyi
ORCID: https://orcid.org/0000-0003-3898-0617 et Labonté, Patrick
ORCID: https://orcid.org/0000-0001-7262-3125
(2024).
Exosomes as Conduits: Facilitating Hepatitis B Virus-Independent Hepatitis D Virus Transmission and Propagation in Hepatocytes
Viruses
, vol. 16
, nº 6.
pp. 1-17.
DOI: 10.3390/v16060825.
Blanchet, Matthieu; Angelo, Léna; Tetreault, Yasmine; Khabir, Marwa; Sureau, Camille; Vaillant, Andrew et Labonté, Patrick
ORCID: https://orcid.org/0000-0001-7262-3125
(2024).
HepG2BD: A Novel and Versatile Cell Line with Inducible HDV Replication and Constitutive HBV Expression
Viruses
, vol. 16
, nº 4:532.
pp. 1-16.
DOI: 10.3390/v16040532.
Blanchet, Matthieu; Angelo, Léna; Tetreault, Yasmine; Khabir, Marwa; Sureau, Camille; Vaillant, Andrew et Labonté, Patrick
ORCID: https://orcid.org/0000-0001-7262-3125
(2023).
An in Vitro Culture Model for The Induction of HDV Replication in a HBV Expressing Cell Line
In: Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD), November 10-14, 2023, Boston, MA.
Fonte, Simone; Plissonnier, :MarieLaure; Michelet, Maud; Blanchet, Matthieu; Labonté, Patrick
ORCID: https://orcid.org/0000-0001-7262-3125; Vaillant, Andrew et Levrero, Massimo
(2023).
Characterization of the Direct Antiviral Effect of REP 2139 on HDV Replication
In: Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD), November 10-14, 2023, Boston, MA.
Sow, Aïssatou Aïcha; Pahmeier, Felix; Ayotte, Yann; Anton, Anaïs; Mazeaud, Clément; Charpentier, Tania; Angelo, Léna; Woo, Simon; Cerikan, Berati; Falzarano, Darryl; Abrahamyan, Levon; Lamarre, Alain
ORCID: https://orcid.org/0000-0002-7913-871X; Labonté, Patrick
ORCID: https://orcid.org/0000-0001-7262-3125; Cortese, Mirko; Bartenschlager, Ralf; Laplante, Steven
ORCID: https://orcid.org/0000-0003-2835-5789 et Chatel-Chaix, Laurent
ORCID: https://orcid.org/0000-0002-7390-8250
(2023).
N-Phenylpyridine-3-Carboxamide and 6-Acetyl-1H-Indazole Inhibit the RNA Replication Step of the Dengue Virus Life Cycle
Antimicrobial Agents and Chemotherapy
, vol. 67
, nº 2.
pp. 1-14.
DOI: 10.1128/aac.01331-22.
Angelo, Léna; Vaillant, Andrew; Blanchet, Matthieu et Labonté, Patrick
ORCID: https://orcid.org/0000-0001-7262-3125
(2023).
Pangenomic antiviral effect of REP 2139 in CRISPR/Cas9 engineered cell lines expressing hepatitis B virus surface antigen
PLoS ONE
, vol. 18
, nº 11.
pp. 1-15.
DOI: 10.1371/journal.pone.0293167.
Angelo, Léna; Blanchet, Matthieu; Vaillant, Andrew et Labonté, Patrick
ORCID: https://orcid.org/0000-0001-7262-3125
(2022).
Defining The Mechanism-of-Action of the Hsp40 Chaperones DNAJB12 and DNAJB14 in the Assembly and Secretion of Hepatitis B Subviral Particles
In: AASLD: The Liver Meeting, Novembre 4-8, 2022, Washington D.C., USA and Virtual.
Angelo, Léna; Boulon, Richard; Blanchet, Matthieu; Vaillant, Andrew et Labonté, Patrick
ORCID: https://orcid.org/0000-0001-7262-3125
(2022).
Identification of the Hsp40 Chaperone DNAJB12 in the Functional Mechanism of the Nucleic Acid Polymer REP 2139
In: AASLD: The Liver Meeting, November, 4-8 2022, Washington D.C., USA and Virtual.
Adejumo, Adeyinka Charles; Labonté, Patrick
ORCID: https://orcid.org/0000-0001-7262-3125 et Bukong, Terence Ndonyi
ORCID: https://orcid.org/0000-0003-3898-0617
(2021).
Relationship Between Recreational Cannabis Use and Helicobacter pylori Infection
Cannabis Cannabinoid Reserch
.
DOI: 10.1089/can.2021.0139.
(Sous Presse)
Angelo, Léna; Blanchet, Matthieu; Vaillant, Andrew et Labonté, Patrick
ORCID: https://orcid.org/0000-0001-7262-3125
(2020).
Activity of REP 2139 in HepG2 Cells Expressing HBsAg Isoforms
In: 19th Annual International Congress of the International Liver Transplantation Society, 12-15 June 2020, Sydnay, Australie.
Angelo, Léna; Blanchet, Matthieu; Vaillant, Andrew et Labonté, Patrick
ORCID: https://orcid.org/0000-0001-7262-3125
(2020).
Activity of REP 2139 in HepG2 Cells Expressing HBsAg Isoforms
In: Liver Meeting of the American Association for the Study of Liver Diseases (AASLD), 2020, November 13 - 16, Electronic Network.
Boulon, Richard; Blanchet, Matthieu; Lemasson, Matthieu; Vaillant, Andrew et Labonté, Patrick
ORCID: https://orcid.org/0000-0001-7262-3125
(2020).
Characterization of the antiviral effects of REP 2139 on the HBV lifecycle in vitro
Antiviral Research
, vol. 183
, nº 104853.
pp. 1-7.
DOI: 10.1016/j.antiviral.2020.104853.
Khabir, Marwa; Aliche, Asma Zahra; Sureau, Camille; Blanchet, Matthieu et Labonté, Patrick
ORCID: https://orcid.org/0000-0001-7262-3125
(2020).
HDV alters the autophagy process to promote its genome replication
Journal of Virology
, vol. 94
, nº 4.
pp. 1-16.
DOI: 10.1128/JVI.01936-19.
Khabir, Marwa; Aliche, Asma Zahra; Sureau, Camille; Blanchet, Matthieu et Labonté, Patrick
ORCID: https://orcid.org/0000-0001-7262-3125
(2020).
Hepatitis Delta Virus Alters the Autophagy Process To Promote Its Genome Replication
Journal of virology
, vol. 94
, nº 4.
pp. 1-16.
DOI: 10.1128/JVI.01936-19.
Dlim, Marwa; Shahout, Fatma; Khabir, Marwa; Labonté, Patrick
ORCID: https://orcid.org/0000-0001-7262-3125 et Laplante, Steven
ORCID: https://orcid.org/0000-0003-2835-5789
(2019).
Revealing Drug Self-Associations into Nano-Entities
ACS Omega
, vol. 4
, nº 5.
pp. 8919-8925.
DOI: 10.1021/acsomega.9b00667.
Blanchet, Matthieu; Sinnathamby, Vigigah; Vaillant, Andrew et Labonté, Patrick
ORCID: https://orcid.org/0000-0001-7262-3125
(2019).
Inhibition of HBsAg secretion by nucleic acid polymers in HepG2.2.15 cells
Antiviral Research
, vol. 164
.
pp. 97-105.
DOI: 10.1016/j.antiviral.2019.02.009.
Li, Jingjing; Abosmaha, Ebtisam; Labonté, Patrick
ORCID: https://orcid.org/0000-0001-7262-3125 et Bukong, Terence Ndonyi
(2019).
Reticulon-3 Modulates the Specific Incorporation of Replication Competent Hepatitis C Virus Molecules for Release Via Exosomes
In: Liver Meeting of the American Association for the Study of Liver Diseases (AASLD), 8-12 November 2019, Boston, Ma.
Fahmy, Ahmed Mohamed; Khabir, Marwa; Blanchet, Matthieu et Labonté, Patrick
ORCID: https://orcid.org/0000-0001-7262-3125
(2018).
LC3B is not recruited along with the autophagy elongation complex (ATG5-12/16L1) at HCV replication site and is dispensable for viral replication
PLoS ONE
, vol. 13
, nº 10:e0205189.
pp. 1-22.
DOI: 10.1371/journal.pone.0205189.
Fahmy, Ahmed Mohamed et Labonté, Patrick
(2017).
The autophagy elongation complex (ATG5-12/16L1) positively regulates HCV replication and is required for wild-type membranous web formation
Scientific Reports
, vol. 7
, nº 40351.
pp. 1-13.
DOI: 10.1038/srep40351.
Lamine-Ajili, Asma; Fahmy, Ahmed Mohamed; Létourneau, Myriam; Chatenet, David; Labonté, Patrick; Vaudry, David et Fournier, Alain
(2016).
Effect of the pituitary adenylate cyclase-activating polypeptide on the autophagic activation observed in in vitro and in vivo models of Parkinson's disease
Biochimica et Biophysica Acta - Molecular Basis of Disease
, vol. 1862
, nº 4.
pp. 688-695.
DOI: 10.1016/j.bbadis.2016.01.005.
Blanchet, Matthieu; Le, Quoc-Tuan; Seidah, Nabil G. et Labonté, Patrick
(2016).
Statins can exert dual, concentration dependent effects on HCV entry in vitro
Antiviral Research
, vol. 128
.
pp. 43-48.
DOI: 10.1016/j.antiviral.2016.02.006.
Le, Quoc-Tuan; Blanchet, Matthieu; Seidah, Nabil G. et Labonté, Patrick
(2015).
Plasma Membrane Tetraspanin CD81 Complexes with Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) and Low Density Lipoprotein Receptor (LDLR), and Its Levels Are Reduced by PCSK9
Journal of Biological Chemistry
, vol. 290
, nº 38.
pp. 23385-23400.
DOI: 10.1074/jbc.M115.642991.
Blanchet, Matthieu; Sureau, Camille; Guévin, Carl; Seidah, Nabil G. et Labonté, Patrick
(2015).
SKI-1/S1P inhibitor PF-429242 impairs the onset of HCV infection
Antiviral Research
, vol. 115
.
pp. 94-104.
DOI: 10.1016/j.antiviral.2014.12.017.
Blanchet, Matthieu; Sureau, Camille et Labonté, Patrick
(2014).
Use of FDA approved therapeutics with hNTCP metabolic inhibitory properties to impair the HDV lifecycle
Antiviral Research
, vol. 106
.
pp. 111-115.
DOI: 10.1016/j.antiviral.2014.03.017.
Delpeut, Sebastien; Rudd, Penny A.; Labonté, Patrick
ORCID: https://orcid.org/0000-0001-7262-3125 et von Messling, Véronica
(2012).
Membrane fusion-mediated autophagy induction enhances morbillivirus cell-to-cell spread
Journal of Virology
, vol. 86
, nº 16.
pp. 8527-8535.
DOI: 10.1128/JVI.00807-12.
Blanchet, Matthieu; Seidah, Nabil G. et Labonté, Patrick
ORCID: https://orcid.org/0000-0001-7262-3125
(2012).
SKI-1/S1P inhibition: A promising surrogate to statins to block Hepatitis C virus replication
Antiviral Research
, vol. 95
, nº 2.
pp. 159-166.
DOI: 10.1016/j.antiviral.2012.05.006.
Guévin, Carl; Manna, David; Bélanger, Claudia; Konan, Kouacou V.; Mak, Paul et Labonté, Patrick
ORCID: https://orcid.org/0000-0001-7262-3125
(2010).
Autophagy protein ATG5 interacts transiently with the hepatitis C virus RNA polymerase (NS5B) early during infection
Virology
, vol. 405
, nº 1.
pp. 1-7.
DOI: 10.1016/j.virol.2010.05.032.
Guévin, Carl; Lamarre, Alain
ORCID: https://orcid.org/0000-0002-7913-871X et Labonté, Patrick
ORCID: https://orcid.org/0000-0001-7262-3125
(2009).
Novel HCV replication mouse model using human hepatocellular carcinoma xenografts
Antiviral Research
, vol. 84
, nº 1.
pp. 14-22.
DOI: 10.1016/j.antiviral.2009.07.009.
Labonté, Patrick
ORCID: https://orcid.org/0000-0001-7262-3125; Begley, Syntia; Guévin, Carl; Asselin, Marie-Claude; Nassoury, Nasha; Mayer, Gaétan; Prat, Annik et Seidah, Nabil G.
(2009).
PCSK9 impedes hepatitis C virus infection in vitro and modulates liver CD81 expression
Hepatology
, vol. 50
, nº 1.
pp. 17-24.
DOI: 10.1002/hep.22911.
Labonté, Patrick
ORCID: https://orcid.org/0000-0001-7262-3125 et Seidah, Nabil G.
(2008).
Emerging viruses: Risk of pandemic
Expert Review of Anti-Infective Therapy
, vol. 6
, nº 5.
pp. 581-583.
DOI: 10.1586/14787210.6.5.581.
Bengue, Alphonsine Kouassi-M; Kouacou, Marie Jeanne Lohoues; Ekaza, Euloge; Siransy-Bogui, Liliane; N'Golo, Daniel Coulibaly; Labonté, Patrick
ORCID: https://orcid.org/0000-0001-7262-3125 et Dosso, Mireille
(2008).
Hepatitis C virus infection in Abidjan Cote d Ivoire: heterogeneity of genotypes
Scientific Research and Essays
, vol. 3
, nº 4.
pp. 139-142.
Amin, Anthony; Zaccardi, Joe; Mullen, Stanley; Olland, Stephane; Orlowski, Mark; Feld, Boris; Labonté, Patrick
ORCID: https://orcid.org/0000-0001-7262-3125 et Mak, Paul
(2003).
Identification of constrained peptides that bind to and preferentially inhibit the activity of the hepatitis C viral RNA-dependent RNA polymerase
Virology
, vol. 313
, nº 1.
pp. 158-169.
DOI: 10.1016/s0042-6822(03)00313-1.
Labonté, Patrick
ORCID: https://orcid.org/0000-0001-7262-3125; Morin, Nicolas; Bowlin, Terry et Mounir, Samir
(2002).
Basal replication of hepatitis C virus in nude mice harboring human tumor
Journal of Medical Virology
, vol. 66
, nº 3.
pp. 312-319.
DOI: 10.1002/jmv.2147.
Labonté, Patrick
ORCID: https://orcid.org/0000-0001-7262-3125; Axelrod, Vladimir; Agarwal, Atul; Aulabaugh, Ann; Amin, Anthony et Mak, Paul
(2002).
Modulation of hepatitis C virus RNA-dependent RNA polymerase activity by structure-based site-directed mutagenesis
Journal of Biological Chemistry
, vol. 277
, nº 41.
pp. 38838-38846.
DOI: 10.1074/jbc.M204657200.
Mak, Paul; Palant, Olga; Labonté, Patrick
ORCID: https://orcid.org/0000-0001-7262-3125 et Plotch, Steve
(2001).
Reconstitution of hepatitis C virus protease activities in yeast
FEBS Letters
, vol. 503
, nº 1.
pp. 13-18.
DOI: 10.1016/s0014-5793(01)02678-3.
Labonté, Patrick
ORCID: https://orcid.org/0000-0001-7262-3125; Kadhim, Salam; Bowlin, Terry et Mounir, Samir
(2000).
Inhibition of tumor growth with doxorubicin in a new orthotopically implanted human hepatocellular carcinoma model
Hepatology Research
, vol. 18
, nº 1.
pp. 72-85.
DOI: 10.1016/s1386-6346(99)00087-x.
Labonté, Patrick
(1995).
Identification et caractérisation de la protéine codée par le gène NS2 de corona virus humain de souche OC43
Mémoire.
Québec, Université du Québec, Institut national de la recherche scientifique, Maîtrise en virologie et immunologie, 166 p.
Blanchet, Matthieu; Sureau, Camille et Labonté, Patrick
.
Identification d’inhibiteurs du NTCP capables de bloquer l’infection d’hepatocytes par les virus des l’hépatites B et Delta
In: 8e édition, Congrès Armand-Frappier 2013, 14-16 novembre 2013, Orford (Québec).
Perks, Alain et Labonté, Patrick
.
Le blocage de la fusion du lysosome avec l’autophagosome par la protéine NS4B du virus de l’hépatite C mène à un flux autophagique incomplet
In: 8e édition, Congrès Armand-Frappier 2013, 14-16 novembre 2013, Orford (Québec).
Fahmy, Ahmed Mohamed et Labonté, Patrick
.
Le complexe d'élongation de l'autophagie (ATG5-12 / 16L1) régule positivement la réplication
du VHC et est nécessaire pour la formation d'usines de réplication de type sauvage
In: 9e édition, Congrès Armand-Frappier 2015, 12-14 novembre 2015, Orford (Québec).
Fahmy, Ahmed Mohamed; Duguay, Christian; Blanchet, Matthieu et Labonté, Patrick
.
Le recrutement du complexe d'élongation d'autophagie (ATG5-12/16) au niveau du site de la réplication du virus de l'hépatite C est nécessaire pour une réplication efficace
In: 8e édition, Congrès Armand-Frappier 2013, 14-16 novembre 2013, Orford (Québec).
Le, Tuan Quoc; Blanchet, Matthieu et Labonté, Patrick
.
Rôle de PCSK9 dans l’expression des récepteurs du virus hepatite C
In: 8e édition, Congrès Armand-Frappier 2013, 14-16 novembre 2013, Orford (Québec).
Boulon, Richard; Blanchet, Matthieu; Vaillant, Andrew et Labonté, Patrick
.
The Hsp40 chaperone DnaJB12 is involved in the morphogenesis of HBV spherical subviral particles and is selectively targeted by nucleic acid polymers
In: 19th Annual International Congress of the International Liver Transplantation Society, 8-12 July 2020, Sydnay, Australie.
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