Document quand l'auteur est "Pelletier, Joelle N."

Lemay-St-Denis, Claudèle; Alejaldre, Lorea; Jemouai, Zakaria; Lafontaine, Kiana; St-Aubin, Maxime; Hitache, Katia; Valikhani, Donya; Weerasinghe, Nuwani W; Létourneau, Myriam; Thibodeaux, Christopher J; Doucet, Nicolas ORCID: https://orcid.org/0000-0002-1952-9380; Baron, Christian; Copp, Janine N et Pelletier, Joelle N. (2023). A conserved SH3-like fold in diverse putative proteins tetramerizes into an oxidoreductase providing an antimicrobial resistance phenotype Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences , vol. 378 , nº 1871:202. pp. 1-14. DOI: 10.1098/rstb.2022.0040.

Lemay-St-Denis, Claudèle; Doucet, Nicolas ORCID: https://orcid.org/0000-0002-1952-9380 et Pelletier, Joelle N. (2022). Integrating dynamics into enzyme engineering Protein Engineering, Design and Selection , vol. 35 , nº gzac015. pp. 1-11. DOI: 10.1093/protein/gzac015.

Gobeil, Sophie; Ebert, Maximilian; Park, Jaeok; Gagné, Donald; Doucet, Nicolas ORCID: https://orcid.org/0000-0002-1952-9380; Berghuis, Albert M.; Pleiss, Jürgen et Pelletier, Joelle N. (2019). The Structural Dynamics of Engineered beta-Lactamases Vary Broadly on Three Timescales yet Sustain Native Function Scientifc Reports , vol. 9 , nº 6656. pp. 1-12. DOI: 10.1038/s41598-019-42866-8.

Gobeil, Sophie; Gagné, Donald; Doucet, Nicolas ORCID: https://orcid.org/0000-0002-1952-9380 et Pelletier, Joelle N. (2016). 15N, 13C and 1H backbone resonance assignments of an artificially engineered TEM-1/PSE-4 class A β-lactamase chimera and its deconvoluted mutant Biomolecular NMR Assignments , vol. 10 , nº 1. pp. 93-99. DOI: 10.1007/s12104-015-9645-8.

Gobeil, Sophie; Clouthier, Christopher M.; Park, Jaeok; Gagné, Donald; Berghuis, Albert M.; Doucet, Nicolas et Pelletier, Joelle N. (2014). Maintenance of Native-like Protein Dynamics May Not Be Required for Engineering Functional Proteins Chemistry and Biology , vol. 21 , nº 10. pp. 1330-1340. DOI: http://dx.doi.org/ 10.1016/j.chembiol.2014.07.016.

Gobeil, Sophie; Park, Jaeok; Clouthier, Christopher M.; Doucet, Nicolas ORCID: https://orcid.org/0000-0002-1952-9380; Berghuis, Albert M. et Pelletier, Joelle N. (2012). Structure-based recombination of beta-lactamases: functional, structural and dynamic investigation of artificially-evolved enzymes In: 26th Annual Symposium of the Protein-Society, August 5–8, 2012, San Diego, California,.

Doucet, Nicolas ORCID: https://orcid.org/0000-0002-1952-9380 et Pelletier, Joelle N. (2009). Gaining Insight into Enzyme Function through Correlation with Protein Motions In: Protein Engineering Handbook. Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Federal Republic of Germany, pp. 187-211.

De Wals, Pierre-Yves; Doucet, Nicolas ORCID: https://orcid.org/0000-0002-1952-9380 et Pelletier, Joelle N. (2009). High tolerance to simultaneous active-site mutations in TEM-1 beta-lactamase: Distinct mutational paths provide more generalized beta-lactam recognition Protein Science , vol. 18 , nº 1. pp. 147-160. DOI: 10.1002/pro.25.

Doucet, Nicolas ORCID: https://orcid.org/0000-0002-1952-9380; Savard, Pierre-Yves; Pelletier, Joelle N. et Gagné, Stephane M (2007). NMR investigation of Tyr105 mutants in TEM-1 beta-lactamase: dynamics are correlated with function Journal of Biological Chemistry , vol. 282 , nº 29. pp. 21448-21459. DOI: 10.1074/jbc.M609777200.

Doucet, Nicolas ORCID: https://orcid.org/0000-0002-1952-9380 et Pelletier, Joelle N. (2007). Simulated annealing exploration of an active-site tyrosine in TEM-1 beta-lactamase suggests the existence of alternate conformations Proteins , vol. 69 , nº 2. pp. 340-348. DOI: 10.1002/prot.21485.

Chica, Roberto A; Doucet, Nicolas ORCID: https://orcid.org/0000-0002-1952-9380 et Pelletier, Joelle N. (2005). Semi-rational approaches to engineering enzyme activity: combining the benefits of directed evolution and rational design Current Opinion in Biotechnology , vol. 16 , nº 4. pp. 378-384. DOI: 10.1016/j.copbio.2005.06.004.

Doucet, Nicolas ORCID: https://orcid.org/0000-0002-1952-9380; De Wals, Pierre-Yves et Pelletier, Joelle N. (2004). Site-saturation mutagenesis of Tyr-105 reveals its importance in substrate stabilization and discrimination in TEM-1 beta-lactamase Journal of Biological Chemistry , vol. 279 , nº 44. pp. 46295-46303. DOI: 10.1074/jbc.M407606200.

Gobeil, Sophie; Park, Jaeok; Ebert, Maximilian; Gagné, Donald; Clouthier, Christopher M.; Pleiss, Jürgen; Doucet, Nicolas; Berghuis, Albert M. et Pelletier, Joelle N. . Structure-based recombination of drug resistance enzymes: structural and functional tolerance to new dynamics in artificially-evolved enzymes In: 2nd Protein Engineering Canada Conference (PEC), 17-19 Juin 2016, Ottawa, Canada.