Kâ, Khady; Rousseau, Marie-Claude 
ORCID: https://orcid.org/0000-0001-5215-8086; Tran, Simon D; Henderson, Melanie et Nicolau, Belinda
(2018).
Association between metabolic syndrome and gingival inflammation in obese children
International Journal of Dental Hygiene
, vol. 16
, nº 3.
pp. 397-403.
DOI: 10.1111/idh.12322.
Résumé
BACKGROUND AND OBJECTIVE: Our previous work showed a positive association between metabolic syndrome (MetS) and gingival crevicular fluid (GCF) tumour necrosis factor-alpha (TNF-alpha) in a sample of obese and non-obese children. However, whether this association persists among obese children is unknown. We aim to investigate the extent to which MetS is associated with GCF TNF-alpha level among obese children.
METHODOLOGY: We performed a cross-sectional analysis using data from visit 1 of the Quebec Adipose and Lifestyle InvesTigation in Youth cohort. A total of 219 obese children aged 8-10 years, for whom data were available for both MetS and TNF-alpha, were included in our analysis. The independent variable, MetS, was defined according to the International Diabetes Federation recommendations. GCF samples were collected from the gingival sulcus using a paper strip, and the concentration of TNF-alpha was determined by enzyme-linked immunosorbent assay. Analyses included descriptive statistics and sex-specific linear regression analyses adjusting for potential confounders.
RESULTS: In this sample comprising only obese children, 24 (10.9%) had MetS. Among obese boys, those with MetS had 44.9% higher GCF TNF-alpha (95% confidence interval: 16.5%-73.3%) compared to those without MetS. No such association was detected in obese girls.
CONCLUSION: MetS was positively associated with GCF TNF-alpha concentration in obese boys. These results suggest that obese boys with MetS may have a worse gingival health profile compared to their obese counterpart without MetS.
| Type de document: | Article |
|---|---|
| Mots-clés libres: | children; metabolic syndrome; tumour necrosis factor‐alpha |
| Centre: | Centre INRS-Institut Armand Frappier |
| Date de dépôt: | 26 mars 2019 05:22 |
| Dernière modification: | 16 févr. 2022 14:54 |
| URI: | https://espace.inrs.ca/id/eprint/6731 |
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