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Canada's contributions to RNA research: past, present and future perspectives

Lécuyer, Eric; Sauvageau, Martin; Kothe, Ute; Unrau, Peter J; Damha, Masad J; Perreault, Jonathan ORCID logoORCID: https://orcid.org/0000-0003-4726-6319; Abou Elela, Sherif; Bayfield, Mark; Claycomb, Julie et Scott, Michelle S (2024). Canada's contributions to RNA research: past, present and future perspectives Biochimie et biologie cellulaire , vol. ahead . DOI: 10.1139/bcb-2024-0176. (Sous Presse)

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Résumé


The field of RNA research has provided of profound insights into the basic mechanisms modulating the function and adaption of biological systems. RNA has also been at the center stage in the development of transformative biotechnological and medical applications, perhaps most notably was the advent of mRNA vaccines that were critical in helping humanity through the Covid-19 pandemic. Unbeknownst to many, Canada boasts a diverse community of RNA scientists, spanning multiple disciplines and locations, whose cutting-edge research has established a rich track-record of contributions across various aspects of RNA science over many decades. Through this position paper, we seek to highlight key contributions made of by Canadian investigators to the RNA field, via both thematic and historical viewpoints. We also discuss initiatives underway to organize and enhance the impact of the Canadian RNA research community, particularly focusing on the creation of the not-for-profit organization RNA Canada ARN. Considering the strategic importance of RNA research in biology and medicine, and its considerable potential to help address major challenges facing humanity, sustained support of this sector will be critical to help Canadian scientists play key roles in the ongoing RNA revolution and the many benefits this could bring about to Canada.

Type de document: Article
Mots-clés libres: RNA Therapeutics; RNA Canada ARN Organization; Canadian RNA Research Contributions; RNA Regulation; RNA Experimentation and Computation
Centre: Centre INRS-Institut Armand Frappier
Date de dépôt: 29 sept. 2024 05:28
Dernière modification: 29 sept. 2024 05:28
URI: https://espace.inrs.ca/id/eprint/15983

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