Aghigh, Arash; Cardot, Jysiane; Mohammadi, Melika Saadat; Jargot, Gaetan; Ibrahim, Heide; Plante, Isabelle 
ORCID: https://orcid.org/0000-0003-2080-6450 et Légaré, François ORCID: https://orcid.org/0000-0002-3065-7156
(2024).
Accelerating whole-sample polarization-resolved second harmonic generation imaging in mammary gland tissue via generative adversarial networks
Biomedical Optics Express
, vol. 15
, nº 9.
pp. 5251-5271.
DOI: 10.1364/BOE.529779..
Résumé
Polarization second harmonic generation (P-SHG) imaging is a powerful technique for studying the structure and properties of biological and material samples. However, conventional whole-sample P-SHG imaging is time consuming and requires expensive equipment. This paper introduces a novel approach that significantly improves imaging resolution under conditions of reduced imaging time and resolution, utilizing enhanced super-resolution generative adversarial networks (ESRGAN) to upscale low-resolution images. We demonstrate that this innovative approach maintains high image quality and analytical accuracy, while reducing the imaging time by more than 95%. We also discuss the benefits of the proposed method for reducing laser-induced photodamage, lowering the cost of optical components, and increasing the accessibility and applicability of P-SHG imaging in various fields. Our work significantly advances whole-sample mammary gland P-SHG imaging and opens new possibilities for scientific discovery and innovation.
| Type de document: | Article |
|---|---|
| Mots-clés libres: | - |
| Centre: | Centre Énergie Matériaux Télécommunications Centre INRS-Institut Armand Frappier |
| Date de dépôt: | 26 déc. 2024 15:50 |
| Dernière modification: | 26 déc. 2024 15:50 |
| URI: | https://espace.inrs.ca/id/eprint/15967 |
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