Tavera-Mendoza, Luz; Ruby, Sylvia; Brousseau, Pauline; Fournier, Michel; Cyr, Daniel et Marcogliese, David (2002). Response of the amphibian tadpole Xenopus laevis to atrazine during sexual differentiation of the ovary Environmental Toxicology and Chemistry , vol. 21 , nº 6. pp. 1264-1267. DOI: 10.1897/1551-5028(2002)021<0527:rotatx>2.0.co;2.
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Xenopus laevis tadpoles (stage 56) were exposed to 21 mug/L atrazine under laboratory-controlled conditions in a static system. Following a 48-h exposure period at 21 +/- 0.5degreesC during sexual differentiation, tadpoles were fixed, and the kidney-gonad complex was microdissected. Quantitative histological analysis revealed in atrazine-exposed ovaries a significant (p < 0.05) increase in frequency of secondary oogonia. Atresia, or oogonial resorption of both primary and secondary oogonia, also increased significantly (p < 0.05). The results suggest that these primary germ cells, which constitute the total number of germ cells in the ovary for the reproductive life of the organism, were reduced by 20% following a 48-h exposure period compared to 2% in controls.
| Type de document: | Article |
|---|---|
| Mots-clés libres: | - |
| Centre: | Centre INRS-Institut Armand Frappier |
| Date de dépôt: | 27 févr. 2025 19:47 |
| Dernière modification: | 27 févr. 2025 19:47 |
| URI: | https://espace.inrs.ca/id/eprint/15202 |
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