Sanderson, Thomas 
ORCID: https://orcid.org/0000-0002-3190-2811
(2009).
Placental and fetal steroidogenesis
In:
Human Embryogenesis: Methods and Protocols.
Methods in Molecular Biology, 550
(550).
Humana Press, Totowa, NJ, pp. 127-136.
Résumé
Steroid hormones are essential for maintenance of pregnancy and fetal development. The expression and catalytic activity of the key steroidogenic enzymes involved in the production of progesterone and estrogens increase during pregnancy, and there is an intricate communication between the mother, the placenta, and the fetus in order to maintain a balanced supply of the steroid hormones essential for embryogenesis. This chapter describes methods for the measurement of the expression and catalytic activity of three key cytochrome P450 (CYP) enzymes involved in the production of progesterone and estrogens, aromatase (CYP19), steroid 17-hydroxylase/17,20-lyase (CYP17), and cholesterol side-chain cleavage (CYP11A).
| Type de document: | Chapitre de livre |
|---|---|
| Mots-clés libres: | - |
| Centre: | Centre INRS-Institut Armand Frappier |
| Date de dépôt: | 07 juill. 2025 18:45 |
| Dernière modification: | 07 juill. 2025 18:45 |
| URI: | https://espace.inrs.ca/id/eprint/15154 |
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