Pintos, Javier; Parent, Marie-Élise 
ORCID: https://orcid.org/0000-0002-4196-3773; Rousseau, Marie-Claude ORCID: https://orcid.org/0000-0001-5215-8086; Case, Bruce W et Siemiatycki, Jack
(2008).
Occupational exposure to asbestos and man-made vitreous fibers, and risk of lung cancer: evidence from two case-control studies in Montreal, Canada
Journal of Occupational and Environmental Medicine
, vol. 50
, nº 11.
pp. 1273-1281.
DOI: 10.1097/JOM.0b013e31818345bb.
Résumé
OBJECTIVE: To examine the effects of occupational asbestos and man-made vitreous fibers (MMVF) on the risk of lung cancer in two population-based case-control studies entailing exposure at lower levels than in historic cohort studies.
METHODOLOGY: Study I (1979 to 1986) comprised 857 cases and 1066 population and cancer controls. Study II (1996 to 2001) comprised 858 cases and 1295 population controls. A detailed job history was obtained to evaluate lifetime occupational exposure to 294 agents, including asbestos and MMVF.
RESULTS: We found increased risks for substantial exposure to asbestos (odds ratio = 1.78; 95% confidence interval: 0.94 to 3.36). The corresponding odds ratio for substantial exposure to MMVF was 1.10 (95% confidence interval: 0.37 to 3.22).
DISCUSSION: Low and moderate levels of exposure to asbestos, as encountered in this population, were associated with some excess risk of lung cancer. Results for MMVF were inconclusive.
| Type de document: | Article |
|---|---|
| Mots-clés libres: | - |
| Centre: | Centre INRS-Institut Armand Frappier |
| Date de dépôt: | 02 août 2024 14:20 |
| Dernière modification: | 02 août 2024 14:20 |
| URI: | https://espace.inrs.ca/id/eprint/15065 |
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