Pintos, Javier; Parent, Marie-Élise 
ORCID: https://orcid.org/0000-0002-4196-3773; Case, Bruce W; Rousseau, Marie-Claude ORCID: https://orcid.org/0000-0001-5215-8086 et Siemiatycki, Jack
(2009).
Risk of mesothelioma and occupational exposure to asbestos and man-made vitreous fibers: evidence from two case-control studies in Montreal, Canada
Journal of Occupational and Environmental Medicine
, vol. 51
, nº 10.
pp. 1177-1184.
DOI: 10.1097/JOM.0b013e3181b68cef.
Résumé
OBJECTIVE: To examine the effects of exposure to occupational asbestos and man-made vitreous fibers (MMVF) across a wide range of occupations on risk of mesothelioma.
METHODOLOGY: Two population-based case-control studies (1979-1986 and 1996-2001) provided 35 histologically confirmed mesothelioma cases and 1965 controls. A detailed job history was obtained to evaluate occupational exposure to many agents, including asbestos and MMVF.
RESULTS: The mesothelioma odds ratio for exposure to any asbestos type was 3.7 (95% confidence interval = 1.7 to 7.8). The subset exposed to amphibole fibers experienced an odds ratio = 7.0 (95% confidence interval = 2.7 to 18.5). Effects of MMVF could not be disentangled from those of asbestos.
DISCUSSION: In workers with exposure levels lower than in most historical cohort studies and across a wide range of industries, a strong association was found between asbestos, especially when it was amphibole, and mesothelioma.
| Type de document: | Article |
|---|---|
| Mots-clés libres: | - |
| Centre: | Centre INRS-Institut Armand Frappier |
| Date de dépôt: | 01 juill. 2024 03:02 |
| Dernière modification: | 01 juill. 2024 03:02 |
| URI: | https://espace.inrs.ca/id/eprint/15064 |
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