Cyr, Daniel G. 
ORCID: https://orcid.org/0000-0002-6566-783X
(2001).
Understanding cell-cell interactions in the epididymis: Key determinants for structural integrity and spermatozoal maturation
National Journal of Andrology (Zhonghua Nankexue)
, vol. 7
, nº 6.
pp. 351-357.
Résumé
A review. Cell-cell interactions in the epididymis are mediated by adhering junctions which are necessary for cell adhesion and tight junctions which form the blood-epididymal barrier. The regulation of these cellular junctions is thought to represent a key determinant in the process of spermatozoal maturation within the epididymis. Tight junctions between adjacent principal cells enable the formation of a specific microenvironment in the lumen of the epididymis that is essential for spermatozoal maturation. Understanding the regulation of these cellular interactions should allow us to better understand the role of the epididymis in spermatozoal maturation and provide tools to manipulate these interactions in order to eventually modulate epididymal function and consequently the maturation process. This review will examine the current state of knowledge of both adhering junctions and tight junctions in the epididymis.
| Type de document: | Article |
|---|---|
| Mots-clés libres: | - |
| Centre: | Centre INRS-Institut Armand Frappier |
| Date de dépôt: | 07 mars 2025 21:08 |
| Dernière modification: | 07 mars 2025 21:08 |
| URI: | https://espace.inrs.ca/id/eprint/14526 |
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