Cellier, Mathieu ORCID: https://orcid.org/0000-0002-6084-434X; Courville, Pascal et Campion, Carole (2007). Nramp1 phagocyte intracellular metal withdrawal defense Microbes and Infection , vol. 9 , nº 14-15. pp. 1662-1670. DOI: 10.1016/j.micinf.2007.09.006.
Ce document n'est pas hébergé sur EspaceINRS.Résumé
Natural resistance-associated macrophage proteins (Nramp) are multispecific symporters facilitating proton-dependent import of divalent metals. Nramp1 restricts microbial access to essential micro-nutrients such as iron and manganese within professional phagosomes. Increased understanding of Nramp1 roles in human phagocytes will be useful for future therapeutic approaches against selected infectious and immune diseases.
Type de document: | Article |
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Mots-clés libres: | Divalent cations; Transport proteins; Phagosomes |
Centre: | Centre INRS-Institut Armand Frappier |
Date de dépôt: | 22 oct. 2024 19:46 |
Dernière modification: | 22 oct. 2024 19:46 |
URI: | https://espace.inrs.ca/id/eprint/14478 |
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