Cellier, Mathieu 
ORCID: https://orcid.org/0000-0002-6084-434X; Courville, Pascal et Campion, Carole
(2007).
Nramp1 phagocyte intracellular metal withdrawal defense
Microbes and Infection
, vol. 9
, nº 14-15.
pp. 1662-1670.
DOI: 10.1016/j.micinf.2007.09.006.
Résumé
Natural resistance-associated macrophage proteins (Nramp) are multispecific symporters facilitating proton-dependent import of divalent metals. Nramp1 restricts microbial access to essential micro-nutrients such as iron and manganese within professional phagosomes. Increased understanding of Nramp1 roles in human phagocytes will be useful for future therapeutic approaches against selected infectious and immune diseases.
| Type de document: | Article |
|---|---|
| Mots-clés libres: | Divalent cations; Transport proteins; Phagosomes |
| Centre: | Centre INRS-Institut Armand Frappier |
| Date de dépôt: | 22 oct. 2024 19:46 |
| Dernière modification: | 22 oct. 2024 19:46 |
| URI: | https://espace.inrs.ca/id/eprint/14478 |
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