Parent, Marie-Élise 
ORCID: https://orcid.org/0000-0002-4196-3773; Siemiatycki, Jack; Latreille, Benoît et Désy, Marie
(2005).
Is occupational physical activity associated with cancer risk among men?
In: Joint Meeting of the Society for Epidemiologic Research/Canadian Society for Epidemiology and Biostatistics, June 27-30, 2005, Toronto, Canada.
Résumé
High physical activity levels might exert a protective effect against certain
cancers through a modulation of hormone levels, growth factors or immune
function. However, the epidemiological evidence for such an association
remains largely unclear. We present here results from an analysis of a population-based case-control study undertaken in Montreal in the 1980s to
investigate the association between occupational and lifestyle factors, and
cancer at several sites. Interviews were carried out with incident male cases
of cancer of the lung (n=857), colon (n=497), bladder (n=484), prostate
(n=449), rectum (n=257), stomach (n=251), kidney (n=177), melanoma
(n=103), esophagus (n=99), pancreas (n=116), liver (n=48), non-Hodgkin's
lymphoma (n=215), Hodgkin's lymphoma (n=54), and 533 population controls. Each job reported by each subject was coded for physical activity levels using metabolic equivalents (METs), calculated based on the metabolic
rate for specific tasks within the job divided by the resting metabolic rate.
Logistic regression analyses were carried out to assess the odds ratio (OR)
and 95% confidence interval (95%CI) for each cancer type associated with
a work history characterized by high physical demand, adjusting for sitespecific potential confounders. As compared to men having held sedentary
jobs (METs of 1.5 or less), the OR for men who had worked in physically
demanding jobs (METs of 4 or more for at least 75% of their work years)
was 0.52 (95%CI=0.29-0.92) for colon, 0.60 (95%CI=0.36--l.02) for prostate, 0.51 (95%CI=0.27--{).96) for bladder cancers, and 0.15 (95%CI=0.03-
0. 77) for melanoma. Trends of lowered risks were also noted for cancers of
the lung (OR=0.82), stomach (OR=0.65), pancreas (OR=0.31), Hodgkin's
(OR=0.58) and non-Hodgkin's (OR=0.61) lymphomas. These findings are
in line with a protective effect of prolonged, high occupational physical
activity levels across a wide range of cancer types.
| Type de document: | Document issu d'une conférence ou d'un atelier |
|---|---|
| Informations complémentaires: | American Journal of Epidemiology 161 (Suppl 1): S93 |
| Mots-clés libres: | - |
| Centre: | Centre INRS-Institut Armand Frappier |
| Date de dépôt: | 12 mars 2024 15:47 |
| Dernière modification: | 12 mars 2024 15:47 |
| URI: | https://espace.inrs.ca/id/eprint/14311 |
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