Stäger, Simona ORCID: https://orcid.org/0000-0001-5508-9565 et Rafati, Sima
(2012).
CD8(+) T cells in leishmania infections: friends or foes?
Frontiers in immunology
, vol. 3
, nº 5.
pp. 1-8.
DOI: 10.3389/fimmu.2012.00005.
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Résumé
Host protection against several intracellular pathogens requires the induction of CD8(+) T cell responses. CD8(+) T cells are potent effector cells that can produce high amounts of pro-inflammatory cytokines and kill infected target cells efficiently. However, a protective role for CD8(+) T cells during Leishmania infections is still controversial and largely depends on the infection model. In this review, we discuss the role of CD8(+) T cells during various types of Leishmania infections, following vaccination, and as potential immunotherapeutic targets.
Type de document: | Article |
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Mots-clés libres: | CD8 T cells; Leishmania; immunology. |
Centre: | Centre INRS-Institut Armand Frappier |
Date de dépôt: | 08 mars 2024 20:16 |
Dernière modification: | 08 mars 2024 20:16 |
URI: | https://espace.inrs.ca/id/eprint/14093 |
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