Differential regulation of the immune response in the spleen and liver of mice infected with leishmania donovani

Stäger, Simona ORCID: https://orcid.org/0000-0001-5508-9565 et Bankoti, Rashmi (2012). Differential regulation of the immune response in the spleen and liver of mice infected with leishmania donovani Journal of Tropical Medicine , vol. 2012 , nº 639304. DOI: 10.1155/2012/639304.

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Résumé

Immunity to pathogens requires generation of effective innate and adaptive immune responses. Leishmania donovani evades these host defense mechanisms to survive and persist in the host. A better understanding and identification of mechanisms that L. donovani employs for its survival is critical for developing novel therapeutic interventions that specifically target the parasite. This paper will highlight some of the mechanisms that the parasite utilizes for its persistence and also discuss how the immune response is regulated.

Type de document:	Article
Mots-clés libres:	-
Centre:	Centre INRS-Institut Armand Frappier
Date de dépôt:	09 mars 2024 18:08
Dernière modification:	09 mars 2024 18:08
URI:	https://espace.inrs.ca/id/eprint/14092

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