Muru, Kevin et Gauthier, Charles 
ORCID: https://orcid.org/0000-0002-2475-2050
(2021).
Glycosylation and Protecting Group Strategies Towards the Synthesis of Saponins and Bacterial Oligosaccharides: A Personal Account
Chemical Record
, vol. 21
, nº 11.
pp. 2990-3004.
DOI: 10.1002/tcr.202000181.
Résumé
Carbohydrates and their conjugates are not only involved in important biological processes but are also regarded as promising therapeutics and prophylactics. Over the last century, several glycosylation methodologies, glycosyl donors, and protecting groups have been developed and some of them have found broad synthetic applications in carbohydrate chemistry. In this Personal Account, we describe how glycosylation and protecting group strategies have been implemented in our as well as in other research groups as to synthesize bioactive glycans, more specifically naturally occurring lupane-type saponins as well as oligosaccharides related to Burkholderia species.
| Type de document: | Article |
|---|---|
| Mots-clés libres: | Oligosaccharides; carbohydrate chemistry; glycosyl donors; protecting groups; saponins |
| Centre: | Centre INRS-Institut Armand Frappier |
| Date de dépôt: | 23 juin 2022 02:39 |
| Dernière modification: | 23 juin 2022 02:39 |
| URI: | https://espace.inrs.ca/id/eprint/12405 |
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