Jantchou, Prévost; Conus, Florence; Richard, Hugues et Rousseau, Marie-Claude . Ascertainment of pediatric inflammatory bowel disease cases from administrative health data in Québec, Canada In: 15th Congress of ECCO, 12-15 February 2020, virtuel.
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Background
Administrative databases are useful for estimating population-level disease occurrence. Our objective was to ascertain cases of pediatric inflammatory bowel disease (IBD) by applying two validated algorithms to administrative health data, evaluate agreement, and compare health services utilization between concordant and discordant cases.
Methods
The Quebec Birth Cohort on Immunity Health was established through linkage of administrative databases and includes 400 611 persons born in the province of Québec (Canada) from 1970-1974. Physician consultations (PC) and hospitalizations (H) for IBD were documented in health databases until 2014. Two validated algorithms were used to identify pediatric IBD cases. Firstly, a single-step algorithm was applied [5PC or 2H within 4 years]. Secondly, a two-step algorithm was implemented, first considering whether the person had undergone sigmoidoscopy/colonoscopy before age 18 [yes: 4PC or 2H within 3 years; no: 7PC or 3H within 3 years]. We evaluated the agreement between both algorithms using the Kappa statistic, and compared health services utilization among concordant and discordant cases using a t-test.
Results
The single-step algorithm generated 527 pediatric IBD cases (0.13%), whereas 480 (0.12%) were identified with the multi-step algorithm. Among the 534 cases identified by either algorithm, 473 (88.6%) were identified by both, 54 (10.1%) only by the single-step, and 7 (1.3%) only by the multi-step algorithm. Kappa was 0.94 (95% confidence interval: 0.92, 0.95), and the proportions of positive and negative agreement were respectively 0.94 and 1.00. The average number of PC and H before age 18 years among concordant and discordant cases was respectively 26.0 and 3.9 (p<0.0001).
Conclusion
The prevalence of pediatric IBD was similar when applying two different case identification algorithms, few cases were discordant. In the near future, a survey conducted in a subset of the cohort will allow us to compare self-report with ascertainment from administrative databases.
| Type de document: | Document issu d'une conférence ou d'un atelier |
|---|---|
| Informations complémentaires: | Affiche scientifique P770 Journal of Crohn's and Colitis, Volume 14, Issue Supplement_1, January 2020, Pages S610–S611, https://doi.org/10.1093/ecco-jcc/jjz203.898 |
| Mots-clés libres: | Diagnosis; Paediatrics and Paediatric to Adult transition; Crohn’s disease; Ulcerative colitis |
| Centre: | Centre INRS-Institut Armand Frappier |
| Date de dépôt: | 14 juill. 2021 15:39 |
| Dernière modification: | 14 juill. 2021 15:39 |
| URI: | https://espace.inrs.ca/id/eprint/11872 |
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