Dépôt numérique

Maple syrup-derived polyphenolics potentiate antibiotics in vivo

Tufenkji, Nathalie, Maisuria, Vimal B, Nguyen, Dao, Déziel, Éric ORCID: https://orcid.org/0000-0002-4609-0115, Casgrain, Pierre-André et Houle, Daniel (2019). Maple syrup-derived polyphenolics potentiate antibiotics in vivo In: 2ND GLOBAL SYMPOSIUM ON CHEMICAL AND BIOLOGICAL EFFECTS OF MAPLE SYRUP PRODUCTS ACS ANNUAL MEETING, 31- 4 March April 2019, Orlando, FL.

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Antibiotic resistance is a rapidly growing threat to global public health. This study looked at the potential of a polyphenolic rich extract from maple syrup (PRMSE) to potentiate the effects of common antibiotics in vivo, which could lessen the need for antibiotic usage. Results indicated that PRMSE and ciprofloxacin combination therapy displayed synergy against P. aeruginosa in and murine infection models at clinically relevant doses, suggesting that PRMSE may have potential as an antibiotic adjuvant for the treatment of different types of bacterial infections

Type de document: Document issu d'une conférence ou d'un atelier
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Centre: Centre INRS-Institut Armand Frappier
Date de dépôt: 20 juill. 2021 23:23
Dernière modification: 07 févr. 2022 15:44
URI: https://espace.inrs.ca/id/eprint/11736

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