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Bioinspired Carbohydrate-Decorated Long-Period Fiber Grating for Label-Free Bacteria Detection.

Celebanska, Anna; Chiniforooshan, Yasser; Janik, Monika; Mikulic, Predrag; Sellamuthu, Balasubramanian; Perreault, Jonathan ORCID logoORCID: https://orcid.org/0000-0003-4726-6319 et Bock, Wojtek J. (2019). Bioinspired Carbohydrate-Decorated Long-Period Fiber Grating for Label-Free Bacteria Detection. IEEE Sensors Journal , vol. 19 , nº 24. pp. 11965-11971. DOI: 10.1109/JSEN.2019.2939279.

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Résumé

Pathogenic bacteria cause thousands of human infections every year. Their effective detection can prevent diseases, decrease the cost of patient hospitalizations, and thus enhance the standard of people's life. Here, we present a bioinspired sensor for bacteria detection in water, which is based on long-period fiber grating (LPFG) and α-mannoside receptor. Embedding of p-aminophenyl-α-D-mannopyranoside, sensitive to E. coli strain, into the biosensor, allows mimicking natural bacteria adhesion to the host cell. The receptor has been covalently immobilized by a thiourea bond to the LPFG platform to ensure stable and reproducible work. The lowest detectable concentration of bacteria was equal to 103 colony forming unit ml -1 .

Type de document: Article
Mots-clés libres: biosensor; bacteria; carbohydrate; long period fiber grating; fiber-optic biosensor; α-mannoside
Centre: Centre Eau Terre Environnement
Date de dépôt: 08 mars 2021 20:39
Dernière modification: 15 févr. 2022 21:06
URI: https://espace.inrs.ca/id/eprint/11385

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