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Evaluation of the effectiveness of anti-influenza vaccination

Pavilanis, Vytautas; Frappier, Armand; Somlo, François; Boudreault, Armand; Claveau, Paul (1958). Evaluation of the effectiveness of anti-influenza vaccination Canadian medical association journal , vol. 79 , nº 7. p. 527-532.

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Résumé

During the winter of 1954-55 we attempted to evaluate in human subjects the effectiveness of a quadrivalent anti-influenza vaccine.

An epidemic of mild influenza affected Montreal in March 1955, and its origin was traced to a virus of antigenic structure identical with that of virus A/Cuppett/50.

The quadrivalent vaccine given in our study led to an appreciable production of antibodies; their titre was quadrupled for strains A/PRS/34 and B/Lee/40 the response being much weaker with strains A/FMI/47 and A/Cuppett/50.

This quadrivalent vaccine conferred a protection against clinical influenza varrying between 40% and 80% according to the group.

Type de document: Article
Informations complémentaires: Recueil de tiré-à-part de la bibliothèque: A0149
Mots-clés libres: effectiveness; efficacite; evaluation; influenza; vaccination
Centre: Centre INRS-Institut Armand Frappier
Date de dépôt: 07 févr. 2020 15:26
Dernière modification: 07 févr. 2020 15:26
URI: http://espace.inrs.ca/id/eprint/8302

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