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Contenu en acides nucleiques de souches de staphylocoques presentant des differences d'antigenicite et de virulence

De Repentigny, Jacques; Sonea, Sorin; Frappier, Armand (1962). Contenu en acides nucleiques de souches de staphylocoques presentant des differences d'antigenicite et de virulence Canadian journal of microbiology , vol. 8 , nº 6. p. 905-913.

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Résumé

In this work, which is a first step in a study on the mechanism of virulence in staphylococci in relation to some of ther genetic factors, two groups of strains were constitued. One group is made of haemolytic, coagulase-positive, and DNase-positive strains, which are virulent for mice by the intracerebral route and the other group of non haemolytic, coagulase-negative, and DNase-negative strains, which are avirulent for mice. Results have shown that the pathogenic group of strains, containing virulence factors, has a lower nucleic acid content (% of dry cells) than the non-pathogenic group.

The two groups of strains are less differentiated by their nucleic acid content than by their coagulase, haemolysin, and DNase activities. A closer correlation seems to exist between this nucleic acid content, and the virulence for mice and also the number of precipitating antigens obtained with staphylococcal antitoxin.

Type de document: Article
Informations complémentaires: Recueil de tiré-à-part de la bibliothèque: A0250
Mots-clés libres: acide; antigénicité; nucléique; souche; staphylocoque; virulence
Centre: Centre INRS-Institut Armand Frappier
Date de dépôt: 06 févr. 2020 16:03
Dernière modification: 06 févr. 2020 16:03
URI: http://espace.inrs.ca/id/eprint/8292

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