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Role d'anticorps-facilitants dans le developpement d'une infection-bacterienne a caractere chronique : la synovite-staphylococcique experimentale du poussin

Forget, Adrien; Borduas, Adrien G.; Richer, Gilles; Frappier, Armand (1970). Role d'anticorps-facilitants dans le developpement d'une infection-bacterienne a caractere chronique : la synovite-staphylococcique experimentale du poussin Revue européenne d'études cliniques et biologiques/European Journal of Clinical and Biological Research , vol. XV , nº 8. p. 895-899.

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Résumé

Nous avons étudié l'influence, d'une part d'un sérum spécifique anti-bourse de Fabricius et d'autre part, d'un sérum homologue anti-staphylococcique dans le développement de la synovite à staphylocoques du poussin. Les résultats obtenus tendent à montrer que des anticorps peuvent faciliter cette infection staphylococcique à caractère chronique chez le poussin.

Abstract

To prevent the production of circulating antibodies we have treated chicken with an antilymphocyte serum specific for the bursa of Fabricius. These chicken manifested an increased resistance to a challenge with a dose of S. aureus which induces a typical lethal staphyloccal synovitis in birds. This anti-serum pre-treatment protected 50% of the chicken while the same bacterial suspension killed all the controls.

We also observed that an homologous anti-staphylococcal serium potentiated the development of the experimental staphylococcal synovitis infect of the chicken. All the chicken injected with a mixture containing this antiserum and a small dos of staphylococci showed signs of synovitis and 80% of them died while, in the control group, the birds injected with the bacterial suspension only, all the birds survived without any clinical sign.

The staphylococcal synovitis of the chick seems, according to these observations, to be enhanced by antibodies which protect the integrity of the bacterial cells thus potentiating the onset of this infection.

We believe that an immune enhancing phenomenon is involved in this chronic type of experimental bacterial infection.

Type de document: Article
Informations complémentaires: Recueil de tiré-à-part de la bibliothèque: A0460
Mots-clés libres: anticorps; anticorps-facilitant; bacterien; chronique; developpement; experimentale; facilitant; infection; infection-bacterienn; poussin; synovite-staphylococ
Centre: Centre INRS-Institut Armand Frappier
Date de dépôt: 05 févr. 2020 21:54
Dernière modification: 05 févr. 2020 21:54
URI: http://espace.inrs.ca/id/eprint/8263

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