Ho, Vikki; Parent, Marie-Élise; Pintos, Javier; Abrahamowicz, Michal; Danieli, Coraline; Richardson, Lesley; Bourbonnais, Robert; Gauvin, Lise; Siemiatycki, Jack et Koushik, Anita (2017). Physical activity and lung cancer risk in men and women Cancer Causes Control , vol. 28 , nº 4. pp. 309-318. DOI: 10.1007/s10552-017-0872-4.
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PURPOSE: Although evidence has accumulated that recreational physical activities (PA) may reduce lung cancer risk, there is little evidence concerning the possible role of a potentially more important source of PA, namely occupational PA. We investigated both recreational and lifetime occupational PA in relation to lung cancer risk in a population-based case-control study in Montreal, Canada (NCASES = 727; NCONTROLS = 1,351). METHODS: Unconditional logistic regression was used to estimate odds ratios (OR), separately for men and women, adjusting for smoking, exposure to occupational carcinogens, and sociodemographic and lifestyle factors. RESULTS: In both sexes, increasing recreational PA was associated with a lower lung cancer risk (ORMEN = 0.66, 95% confidence interval (CI) 0.47-0.92; ORWOMEN = 0.55, 95% CI 0.34-0.88, comparing the highest versus lowest tertiles). For occupational PA, no association was observed among women, while increasing occupational PA was associated with increased risk among men (ORMEN = 1.96, 95% CI 1.27-3.01). ORs were not modified by occupational lung carcinogen exposure, body mass index, and smoking level; results were similar across lung cancer histological types. CONCLUSIONS: Our results support the previous findings for recreational PA and lung cancer risk. Unexpectedly, our findings suggest a positive association for occupational PA; this requires replication and more detailed investigation.
| Type de document: | Article |
|---|---|
| Mots-clés libres: | Case–control studies; Exercise; Histology; Lung neoplasms; Motor activity; Occupation; Recreation |
| Centre: | Centre INRS-Institut Armand Frappier |
| Date de dépôt: | 20 févr. 2019 21:32 |
| Dernière modification: | 16 juin 2023 12:11 |
| URI: | https://espace.inrs.ca/id/eprint/5376 |
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