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Immunotoxicity and genotoxicity of single-walled carbon nanotubes co-exposed with cadmium in the freshwater mussel, Elliptio complanata

Revel, Messika; Fournier, Michel; Robidoux, Pierre Yves (2018). Immunotoxicity and genotoxicity of single-walled carbon nanotubes co-exposed with cadmium in the freshwater mussel, Elliptio complanata Environmental Toxicology and Pharmacology , vol. 62 . p. 177-180. DOI: 10.1016/j.etap.2018.07.008.

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Résumé

Potential immunotoxicity and genotoxicity of as-produced and purified single walled carbon nanotubes (SWCNT, 500 μg L-¹) with or without cadmium (20 μg L-¹) was investigated in hemocytes of the freshwater mussel, Elliptio complanata. Our results showed a decrease in hemocyte viability after 3, and 8 days of exposure and an increase of hemocyte phagocytic efficiency for organisms exposed to Cd. No modification of the cyclo-oxygenase (COX) activity was measured. An increase in DNA damage was measured after 1 day of exposure to Cd and a potentiating effect of combined exposures was observed.

Type de document: Article
Mots-clés libres: Cadmium; DNA damage; Interaction; Mussels; SWCN
Centre: Centre INRS-Institut Armand Frappier
Date de dépôt: 10 mars 2019 19:00
Dernière modification: 10 mars 2019 19:00
URI: http://espace.inrs.ca/id/eprint/7481

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