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Protozoan parasites and Type I IFNs

Silva-Barrios, Sasha; Stäger, Simona (2017). Protozoan parasites and Type I IFNs Frontiers in Immunology , vol. 8 , nº 14. DOI: 10.3389/fimmu.2017.00014.

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Résumé

For many years, the role of interferon (IFN)-I has been characterized primarily in the context of viral infections. However, regulatory functions mediated by IFN-I have also been described against bacterial infections and in tumor immunology. Only recently, the interest in understanding the immune functions mediated by IFN-I has dramatically increased in the field of protozoan infections. In this review, we discuss the discrete role of IFN-I in the immune response against major protozoan infections: Plasmodium, Leishmania, Trypanosoma, and Toxoplasma.

Type de document:
Mots-clés libres: IFN-I; Leishmania; Plasmodium; Protozoan infections; Toxoplasma; Trypanosoma
Centre: Centre INRS-Institut Armand Frappier
Date de dépôt: 25 juin 2017 13:35
Dernière modification: 25 juin 2017 13:35
URI: http://espace.inrs.ca/id/eprint/5436

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