Document quand l'auteur est "Gagné, Donald"

Article

Narayanan, Chitra; Bernard, David N.; Létourneau, Myriam; Gagnon, Jacinthe; Gagné, Donald; Bafna, Khushboo; Calmettes, Charles; Couture, Jean-François; Agarwal, Pratul K et Doucet, Nicolas ORCID: https://orcid.org/0000-0002-1952-9380 (2020). Insights into Structural and Dynamical Changes Experienced by Human RNase 6 upon Ligand Binding Biochemistry , vol. 59 , nº 6. pp. 755-765. DOI: 10.1021/acs.biochem.9b00888.

Gobeil, Sophie; Ebert, Maximilian; Park, Jaeok; Gagné, Donald; Doucet, Nicolas ORCID: https://orcid.org/0000-0002-1952-9380; Berghuis, Albert M.; Pleiss, Jürgen et Pelletier, Joelle N. (2019). The Structural Dynamics of Engineered beta-Lactamases Vary Broadly on Three Timescales yet Sustain Native Function Scientifc Reports , vol. 9 , nº 6656. pp. 1-12. DOI: 10.1038/s41598-019-42866-8.

Gagné, Donald; Narayanan, Chitra; Bafna, Khushboo; Charest, Laurie-Anne; Agarwal, Pratul K et Doucet, Nicolas ORCID: https://orcid.org/0000-0002-1952-9380 (2018). Correction to: Sequence-specific backbone resonance assignments and microsecond timescale molecular dynamics simulation of human eosinophil-derived neurotoxin Biocular NMR Assignements , vol. 12 , nº 2. pp. 365-367. DOI: 10.1007/s12104-018-9833-4.

Narayanan, Chitra; Bernard, David N.; Bafna, Khushboo; Gagné, Donald; Chennubhotla, Chakra; Doucet, Nicolas ORCID: https://orcid.org/0000-0002-1952-9380 et Agarwal, Pratul K (2018). Conservation of Dynamics Associated with Biological Function in an Enzyme Superfamily Structure , vol. 26 , nº 3. pp. 426-436. DOI: 10.1016/j.str.2018.01.015.

Narayanan, Chitra; Gagné, Donald; Reynolds, Kimberly A et Doucet, Nicolas ORCID: https://orcid.org/0000-0002-1952-9380 (2017). Conserved amino acid networks modulate discrete functional properties in an enzyme superfamily Scientific Reports , vol. 7 , nº 1. 3207-1-3207-9. DOI: 10.1038/s41598-017-03298-4.

Gagné, Donald; Narayanan, Chitra; Bafna, Khushboo; Charest, Laurie-Anne; Agarwal, Pratul K et Doucet, Nicolas ORCID: https://orcid.org/0000-0002-1952-9380 (2017). Sequence-specific backbone resonance assignments and microsecond timescale molecular dynamics simulation of human eosinophil-derived neurotoxin Biomolecular NMR Assignments , vol. 11 , nº 2. pp. 143-149. DOI: 10.1007/s12104-017-9736-9.

Herrero, Christian; Nguyen-Thi, Nhung; Hammerer, Fabien; Banse, Frédéric; Gagné, Donald; Doucet, Nicolas ORCID: https://orcid.org/0000-0002-1952-9380; Mahy, Jean-Pierre et Ricoux, Rémy (2016). Photoassisted oxidation of sulfides catalyzed by artificial metalloenzymes using water as an oxygen source Catalysts , vol. 6 , nº 12:202. pp. 1-12. DOI: 10.3390/catal6120202.

Gagné, Donald; Narayanan, Chitra; Nguyen-Thi, Nhung; Roux, Louise D.; Bernard, David N.; Brunzelle, Joseph S.; Couture, Jérôme; Agarwal, Pratul K et Doucet, Nicolas ORCID: https://orcid.org/0000-0002-1952-9380 (2016). Ligand Binding Enhances Millisecond Conformational Exchange in Xylanase B2 from Streptomyces lividans Biochemistry , vol. 55 , nº 30. pp. 4184-96. DOI: 10.1021/acs.biochem.6b00130.

Gobeil, Sophie; Gagné, Donald; Doucet, Nicolas ORCID: https://orcid.org/0000-0002-1952-9380 et Pelletier, Joelle N. (2016). 15N, 13C and 1H backbone resonance assignments of an artificially engineered TEM-1/PSE-4 class A β-lactamase chimera and its deconvoluted mutant Biomolecular NMR Assignments , vol. 10 , nº 1. pp. 93-99. DOI: 10.1007/s12104-015-9645-8.

Vladoiu, Maria Claudia; Labrie, Marilyne; Létourneau, Myriam; Egesborg, Philippe; Gagné, Donald; Billard, Étienne; Grosset, Andrée-Anne; Doucet, Nicolas ORCID: https://orcid.org/0000-0002-1952-9380; Chatenet, David et St-Pierre, Yves (2015). Design of a peptidic inhibitor that targets the dimer interface of a prototypic galectin Oncotarget , vol. 6 , nº 38. pp. 40970-80. DOI: 10.18632/oncotarget.5403.

Gagné, Donald; French, Rachel L; Narayanan, Chitra; Simonović, Miljan; Agarwal, Pratul K et Doucet, Nicolas ORCID: https://orcid.org/0000-0002-1952-9380 (2015). Perturbation of the Conformational Dynamics of an Active-Site Loop Alters Enzyme Activity Structure , vol. 23 , nº 12. pp. 2256-66. DOI: 10.1016/j.str.2015.10.011.

Gagné, Donald et Doucet, Nicolas ORCID: https://orcid.org/0000-0002-1952-9380 (2015). Sequence-specific backbone 1H, 13C, and 15N resonance assignments of human ribonuclease 4 Biomolecular NMR Assignments , vol. 9 , nº 1. pp. 181-185. DOI: 10.1007/s12104-014-9570-2.

Grosset, Andrée-Anne; Labrie, Marilyne; Gagné, Donald; Vladoiu, Maria Claudia; Gaboury, Louis; Doucet, Nicolas et St-Pierre, Yves (2014). Cytosolic galectin-7 impairs p53 functions and induces chemoresistance in breast cancer cells BMC Cancer , vol. 14 . p. 801. DOI: 10.1186/1471-2407-14-801.

Gobeil, Sophie; Clouthier, Christopher M.; Park, Jaeok; Gagné, Donald; Berghuis, Albert M.; Doucet, Nicolas et Pelletier, Joelle N. (2014). Maintenance of Native-like Protein Dynamics May Not Be Required for Engineering Functional Proteins Chemistry and Biology , vol. 21 , nº 10. pp. 1330-1340. DOI: http://dx.doi.org/ 10.1016/j.chembiol.2014.07.016.

Gagné, Donald; Narayanan, Chitra et Doucet, Nicolas (2014). Network of long-range concerted chemical shift displacements upon ligand binding to human angiogenin Protein Science , vol. 24 , nº 4. pp. 525-33. DOI: 10.1002/pro.2613.

Gagné, Donald et Doucet, Nicolas (2013). Structural and functional importance of local and global conformational fluctuations in the RNase A superfamily FEBS Journal , vol. 280 , nº 22. pp. 5596-5607. DOI: http://dx.doi.org/ 10.1111/febs.12371.

Document issu d'une conférence ou d'un atelier

Gagné, Donald; Charest, Laurie-Anne; Kovrigin, Evgenii et Doucet, Nicolas ORCID: https://orcid.org/0000-0002-1952-9380 (2012). Conservation of flexible residue clusters among structural homologues of the ribonuclease family In: 26th Annual Symposium of the Protein-Society Protein Science, May 22-25, 2011, San Diego, California,.

Gagné, Donald; Charest, Laurie-Anne et Doucet, Nicolas . Analyse comparative de la flexibilité des mouvements chez les homologues des RNases humaines In: 8e édition, Congrès Armand-Frappier 2013, 14-16 novembre 2013, Orford (Québec).

Egesborg, Philippe; Bernard, David N.; Urvoas, Agathe; Gagné, Donald; Mahy, Jean-Pierre; Ricoux, Rémy et Doucet, Nicolas . Correlating functional divergence and dynamical variations in the pancreatic-type ribonuclease superfamily In: 2nd Protein Engineering Canada Conference (PEC), 17-19 Juin 2016, Ottawa, Canada.

Nguyen, Thi Tuyet Nhung; Gagné, Donald; Roux, Louise D.; Couture, Jean-François; Agarwal, Pratul K et Doucet, Nicolas . Échanges conformationnels subits par la xylanase B2 de Streptomyces lividans dans sa forme libre et liée In: 9e édition, Congrès Armand-Frappier 2015, 12-14 novembre 2015, Orford (Québec).

Bernard, David N.; Létourneau, Myriam; Gagné, Donald; Groleau, Marie-Christine; Déziel, Éric et Doucet, Nicolas . Effects of Evolutionary Distance on Protein Dynamics, Antibacterial Activity, and Cytotoxicity in Members of the Ribonuclease 3 Subfamily In: 31st Annual Symposium of the Protein-Society, 24-27 juin 2017, Montréal (Québec) Canada.

Bernard, David N.; Gagné, Donald et Doucet, Nicolas . Évolution de la dynamique moléculaire chez des enzymes d’une même famille In: 9e édition, Congrès Armand-Frappier 2015, 12-14 novembre 2015, Orford (Québec).

Egesborg, Philippe; Beauchamp, Stéphane; Gagné, Donald; Grosset, Andrée-Anne; Gaboury, Louis; St-Pierre, Yves et Doucet, Nicolas . Exploration du rôle structurel et fonctionnel de la galectine-7 dans le cancer In: 8e édition, Congrès Armand-Frappier 2013, 14-16 novembre 2013, Orford (Québec).

Gagné, Donald; Nguyen-Thi, Nhung; Narayanan, Chitra; Roux, Louise D.; Brunzelle, Joseph S.; Couture, Jean-François; Agarwal, Pratul K et Doucet, Nicolas . Ligand binding induces enhanced conformational exchange in xylanase B2 from Streptomyces lividans In: 16e Symposium annuel de PROTEO, 13 Mai 2016, Université Laval, Québec, QC.

Egesborg, Philippe; Bernard, David N.; Urvoas, Agathe; Gagné, Donald; Mahy, Jean-Pierre; Ricoux, Rémy et Doucet, Nicolas . Selective binding of functionalized porphyrin compounds at the homodimeric interface of human galectin-7 In: 16e Symposium annuel de PROTEO, Mai 2016, Université Laval, Québec.

Bernard, David N.; Gagné, Donald et Doucet, Nicolas . Similarities between conformational exchange patterns in members of the ribonuclease 3 subfamily In: 16e Symposium annuel de PROTEO, 13 Mai 2016, Université Laval, Québec, QC.

Gagnon, Jacinthe; Sarvan, Sabina; Gagné, Donald; Couture, Jean-François et Doucet, Nicolas . Structural and functional comparison of two human homologues of the RNase A superfamily In: 2nd Protein Engineering Canada Conference (PEC), 17-19 Juin 2016, Ottawa, Canada.

Gobeil, Sophie; Park, Jaeok; Ebert, Maximilian; Gagné, Donald; Clouthier, Christopher M.; Pleiss, Jürgen; Doucet, Nicolas; Berghuis, Albert M. et Pelletier, Joelle N. . Structure-based recombination of drug resistance enzymes: structural and functional tolerance to new dynamics in artificially-evolved enzymes In: 2nd Protein Engineering Canada Conference (PEC), 17-19 Juin 2016, Ottawa, Canada.

Bernard, David N.; Gagné, Donald et Doucet, Nicolas . Uncovering similar conformational exchange residue clusters in eosinophil-like ribonucleases In: 2nd Protein Engineering Canada Conference (PEC), Juin 2016, Ottawa.

Thèse

Gagné, Donald (2015). Conservation et modulation de secteurs dynamiques fonctionnels entre ribonucléases homologues Thèse. Québec, Université du Québec, Institut National de la Recherche Scientifique, Doctorat en biologie, 150 p.