Document quand l'auteur est "Alain, Tommy"

Centre INRS-Institut Armand Frappier

Chaparro, Visnu; Leroux, Louis-Phillipe; Lebourg, Aurore; Chagneau, Sophie; Graber, Tyson E; Alain, Tommy et Jaramillo, Maritza ORCID: https://orcid.org/0000-0002-1910-5684 (2024). Leukemia inhibitory factor drives transcriptional programs that promote lipid accumulation and M2 polarization in macrophages Journal of Leukocyte Biology , vol. 117 , nº qiae178. pp. 1-14. DOI: 10.1093/jleuko/qiae178.

Chaparro, Visnu; Graber, Tyson; Alain, Tommy et Jaramillo, Maritza ORCID: https://orcid.org/0000-0002-1910-5684 (2022). Transcriptional profiling of macrophages reveals distinct parasite stage-driven signatures during early infection by Leishmania donovani Scientific Reports , vol. 12 , nº 6369. pp. 1-13. DOI: 10.1038/s41598-022-10317-6.

Chaparro, Visnu; Graber, Tyson E; Alain, Tommy et Jaramillo, Maritza ORCID: https://orcid.org/0000-0002-1910-5684 (2022). Transcriptional profiling of macrophages reveals distinct parasite stage-driven signatures during early infection by Leishmania donovani Scientific Reports , vol. 12 , nº 6369. pp. 1-13. DOI: 10.1038/s41598-022-10317-6.

Carter-Timofte, Madalina Elena; Arulanandam, Rozanne; Kurmasheva, Naziia; Fu, Kathy; Laroche, Geneviève; Taha, Zaid; van der Horst, Demi; Cassin, Lena; van der Sluis, Renée M; Palermo, Enrico; Di Carlo, Daniele; Jacobs, David; Maznyi, Glib; Azad, Taha; Singaravelu, Ragunath; Ren, Fanghui; Hansen, Anne Louise; Idorn, Manja; Holm, Christian K; Jakobsen, Martin R; van Grevenynghe, Julien ORCID: https://orcid.org/0000-0002-2952-4081; Hiscott, John; Paludan, Søren R; Bell, John Cameron; Séguin, Jean R.; Sabourin, Luc A; Côté, Marceline; Diallo, Jean-Simon; Alain, Tommy et Olagnier, David (2021). Antiviral Potential of the Antimicrobial Drug Atovaquone against SARS-CoV-2 and Emerging Variants of Concern ACS Infectious Diseases , vol. 7 , nº 11. pp. 3034-3051. DOI: 10.1021/acsinfecdis.1c00278.

Pearl, Dana; Katsumura, Sakie; Amiri, Mehdi; Tabatabaei, Negar; Zhang, Xu; Vinette, Valérie; Pang, Xinhe; Beug, Shawn T; Kim, Sung-Hoon; Jones, Laura M; Robichaud, Nathaniel; Ong, Sang-Ging; Jia, Jian-Jun; Ali, Hamza; Tremblay, Michel L; Jaramillo, Maritza ORCID: https://orcid.org/0000-0002-1910-5684; Alain, Tommy; Morita, Masahiro; Sonenberg, Nahum et Tahmasebi, Soroush (2020). 4E-BP-Dependent Translational Control of Irf8 Mediates Adipose Tissue Macrophage Inflammatory Response Journal of Immunology , vol. 204 , nº 9. pp. 2392-2400. DOI: 10.4049/jimmunol.1900538.

Chaparro, Visnu; Leroux, Louis-Phillipe; Masvidal Sanz, Laia; Lorent, Julie; Graber, Tyson; Zimmermann, Aude; Arango Duque, Guillermo; Descoteaux, Albert ORCID: https://orcid.org/0000-0002-0633-5309; Alain, Tommy; Larsson, Ola et Jaramillo, Maritza ORCID: https://orcid.org/0000-0002-1910-5684 (2020). Translational profiling of macrophages infected with Leishmania donovani identifies mTOR- and eIF4A-sensitive immune-related transcripts PLoS Pathogens , vol. 16 , nº 6:e10082. pp. 1-24. DOI: 10.1371/journal.ppat.1008291.

William, Mirtha; Leroux, Louis-Phillipe; Chaparro, Visnu; Graber, Tyson; Alain, Tommy et Jaramillo, Maritza ORCID: https://orcid.org/0000-0002-1910-5684 (2019). Translational repression of Ccl5 and Cxcl10 by 4E-BP1 and 4E-BP2 restrains the ability of mouse macrophages to induce migration of activated T cells European Journal of Immunology , vol. 49 , nº 8. pp. 1200-1212. DOI: 10.1002/eji.201847857.

Hoang, Huy-Dung; Graber, Tyson; Jia, Jian-Jun; Vaidya, Nasana; Gilchrist, Victoria H; Xiang, Xiao; Li, Wencheng; Cowan, Kyle N; Gkogkas, Chistos G; Jaramillo, Maritza ORCID: https://orcid.org/0000-0002-1910-5684; Jafarnejad, Seyed Mehdi et Alain, Tommy (2019). Induction of an Alternative mRNA 5' Leader Enhances Translation of the Ciliopathy Gene Inpp5e and Resistance to Oncolytic Virus Infection Cell Reports , vol. 29 , nº 12. pp. 4010-4023. DOI: 10.1016/j.celrep.2019.11.072.

Zakaria, Chadi; Sean, Polen; Hoang, Huy-Dung; Leroux, Louis-Phillipe; Watson, Margaret; Tekeste Workenhe, Samuel; Hearnden, Jaclyn; Pearl, Dana; Truong, Vinh Tai; Robichaud, Nathaniel; Yanagiya, Akiko; Tahmasebi, Soroush; Jafarnejad, Seyed Mehdi; Jia, Jian-Jun; Pelin, Adrian; Diallo, Jean-Simon; Le Boeuf, Fabrice; Bell, John Cameron; Mossman, Karen Louise; Graber, Tyson; Jaramillo, Maritza ORCID: https://orcid.org/0000-0002-1910-5684; Sonenberg, Nahum et Alain, Tommy (2018). Active-site mTOR inhibitors augment HSV1-dICP0 infection in cancer cells via dysregulated eIF4E/4E-BP axis PLoS Pathogens , vol. 14 , nº 8:e1007264. pp. 1-23. DOI: 10.1371/journal.ppat.1007264.

Leroux, Louis-Phillipe; Lorent, Julie; Graber, Tyson; Chaparro, Visnu; Masvidal Sanz, Laia; Aguirre, Maria; Fonseca, Bruno D.; van Kempen, Léon C.; Alain, Tommy; Larsson, Ola et Jaramillo, Maritza ORCID: https://orcid.org/0000-0002-1910-5684 (2018). The protozoan parasite Toxoplasma gondii selectively reprograms the host cell translatome Infection and Immunity , vol. 86 , nº 9:e00244-18. pp. 1-20. DOI: 10.1128/IAI.00244-18.

William, Mirtha; Leroux, Louis-Phillipe; Chaparro, Visnu; Lorent, Julie; Graber, Tyson; M'Boutchou, Marie-Noël; Charpentier, Tania; Fabié, Aymeric; Dozois, Charles M. ORCID: https://orcid.org/0000-0003-4832-3936; Stäger, Simona ORCID: https://orcid.org/0000-0001-5508-9565; van Kempen, Léon C.; Alain, Tommy; Larsson, Ola et Jaramillo, Maritza ORCID: https://orcid.org/0000-0002-1910-5684 (2018). eIF4E-Binding Proteins 1 and 2 Limit Macrophage Anti-Inflammatory Responses through Translational Repression of IL-10 and Cyclooxygenase-2 Journal of Immunology , vol. 200 , nº 12. pp. 4102-4116. DOI: 10.4049/jimmunol.1701670.

Bhat, Mamatha; Yanagiya, Akiko; Graber, Tyson; Razumilava, Nataliya; Bronk, Steve; Zammit, Domenick; Zhao, Yunhao; Metrakos, Peter; Pollak, Michael; Sonenberg, Nahum; Gores, Gregory; Jaramillo, Maritza; Morita, Masahiro et Alain, Tommy (2017). Metformin requires 4E-BPs to induce apoptosis and repress translation of Mcl-1 in hepatocellular carcinoma cells Oncotarget , vol. 8 , nº 31. pp. 50542-50556. DOI: 10.18632/oncotarget.10671.

Nehdi, Atef; Sean, Polen; Linares, Izzar; Colina, Rodney; Jaramillo, Maritza et Alain, Tommy (2014). Deficiency in Either 4E-BP1 or 4E-BP2 Augments Innate Antiviral Immune Responses PLoS ONE , vol. 9 , nº 12. e114854. DOI: 10.1371/journal.pone.0114854.

Herdy, Barbara; Jaramillo, Maritza ORCID: https://orcid.org/0000-0002-1910-5684; Svitkin, Yuri V.; Rosenfeld, Amy B.; Kobayashi, Mariko; Walsh, Derek; Alain, Tommy; Sean, Polen; Robichaud, Nathaniel; Topisirovic, Ivan; Furic, Luc; Dowling, Ryan J O.; Sylvestre, Annie; Rong, Liwei; Colina, Rodney; Costa-Mattioli, Mauro; Fritz, Jorg H; Olivier, Martin; Brown, Earl; Mohr, Ian et Sonenberg, Nahum (2012). Translational control of the activation of transcription factor NF-kappaB and production of type I interferon by phosphorylation of the translation factor eIF4E Nature Immunology , vol. 13 , nº 6. pp. 543-50. DOI: 10.1038/ni.2291.

Van Themsche, Céline; Alain, Tommy; Kossakowska, Anna E.; Urbanski, Stefan; Potworowski, Edouard F. et St-Pierre, Yves ORCID: https://orcid.org/0000-0002-1948-2041 (2004). Stromelysin-2 (matrix metalloproteinase 10) is inducible in lymphoma cells and accelerates the growth of lymphoid tumors in vivo Journal of Immunology , vol. 173 , nº 6. pp. 3605-3611. DOI: 10.4049/jimmunol.173.6.3605.

De Noncourt, Pascal; Robledo, Olivier; Alain, Tommy; Kossakowska, Anna E.; Urbanski, Stefan J.; Potworowski, Edouard F. et St-Pierre, Yves ORCID: https://orcid.org/0000-0002-1948-2041 (2001). Leukocyte elastase in murine and human non-Hodgkin lymphomas Journal of Leukocyte Biology , vol. 70 , nº 4. pp. 585-591. DOI: 10.1189/jlb.70.4.585.

William, Mirtha; Leroux, Louis-Phillipe; Lorent, Julie; Visnu, C; M'Boutchou, Marie-Noël; Gerber, Tyson; Charpentier, Tania; Fabié, Aymeric; Alain, Tommy; Dozois, Charles M.; Stäger, Simona; van Kempen, Léon C.; Larsson, Ola et Jaramillo, Maritza . Les protéines 4E-BP1 et 2 contrôlent les réponses anti-inflammatoires des macrophages via la répression traductionnelle de l’IL-10 et COX-2 In: Congrès Armand-Frappier 2017 (10e édition), 9-11 novembre 2017, Orford (Québec).