Frappier, Armand; Desjardins, Roger et Panisset, Maurice (1957). Primary resistance of tubercle bacilli to streptomycin and other antituberculous agents in the province of quebec The Canadian Medical Association Jorunal , vol. 76 . pp. 653-655.
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Of 686 cultures of tubercle bacilli, isolated from patients living in there representative geographic areas of the Province of Quebec, prior to any treatment with antibiotics, 10,8% were found resistant to 10 micrograms of streptomycin. This rate is somewhat higher than that reported in the literature. Resistance to PAS, INH-Rimifon, INH-Marsilid and Viomycin varied considerably, by order from 0.6%, 41.1% to 16.4%. The distribution of resistance to streptomycin was pratically equal in each area of the province.
The very high resistance to isopropul form of INH (Marsilid) is attributed to a natural rather than an acquired reistance of the strains of tubercle bacilli tested.
It is suggested that periodic surveys be done in order to check possible increase of drug resistance.
| Type de document: | Article |
|---|---|
| Informations complémentaires: | Recueil de tiré-à-part de la bibliothèque: A0127 |
| Mots-clés libres: | 09-0244839; agent; antituberculous; bacille; quebec; streptomycin; tubercle; tuberculeux |
| Centre: | Centre INRS-Institut Armand Frappier |
| Date de dépôt: | 21 nov. 2019 16:08 |
| Dernière modification: | 21 nov. 2019 16:20 |
| URI: | https://espace.inrs.ca/id/eprint/8306 |
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