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Contenu en acides nucleiques de souches de staphylocoques presentant des differences d'antigenicite et de virulence

De Repentigny, Jacques, Sonea, Sorin et Frappier, Armand (1962). Contenu en acides nucleiques de souches de staphylocoques presentant des differences d'antigenicite et de virulence Canadian journal of microbiology , vol. 8 , nº 6. p. 905-913.

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Résumé

In this work, which is a first step in a study on the mechanism of virulence in staphylococci in relation to some of ther genetic factors, two groups of strains were constitued. One group is made of haemolytic, coagulase-positive, and DNase-positive strains, which are virulent for mice by the intracerebral route and the other group of non haemolytic, coagulase-negative, and DNase-negative strains, which are avirulent for mice. Results have shown that the pathogenic group of strains, containing virulence factors, has a lower nucleic acid content (% of dry cells) than the non-pathogenic group.

The two groups of strains are less differentiated by their nucleic acid content than by their coagulase, haemolysin, and DNase activities. A closer correlation seems to exist between this nucleic acid content, and the virulence for mice and also the number of precipitating antigens obtained with staphylococcal antitoxin.

Type de document: Article
Informations complémentaires: Recueil de tiré-à-part de la bibliothèque: A0250
Mots-clés libres: acide; antigénicité; nucléique; souche; staphylocoque; virulence
Centre: Centre INRS-Institut Armand Frappier
Date de dépôt: 06 févr. 2020 16:03
Dernière modification: 06 févr. 2020 16:03
URI: https://espace.inrs.ca/id/eprint/8292

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