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Cryptosporidium passes the bile acid test to survive

Pardy, Ryan D ORCID logoORCID: https://orcid.org/0000-0002-0024-8888; Karo-Atar, Danielle et King, Irah L (2025). Cryptosporidium passes the bile acid test to survive Trends Parasitology , vol. 41 , nº 11. pp. 950-951. DOI: 10.1016/j.pt.2025.09.006.

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Résumé


Cryptosporidium spp. are an important cause of diarrheal disease worldwide. However, pathogenesis can vary between and within parasite species. Huang et al. identified CpMRP1 as a transporter of the microbial metabolite deoxycholic acid and virulence factor that determines infection outcome in susceptible mice.

Type de document: Article
Informations complémentaires: R.D.P. is supported by a Discovery Grant from the Natural Sciences and Engineering Research Council.
Mots-clés libres: ABC transporter; Cryptosporidium; microbial metabolites; virulence factors
Centre: Centre INRS-Institut Armand Frappier
Date de dépôt: 08 juin 2026 20:08
Dernière modification: 08 juin 2026 20:08
URI: https://espace.inrs.ca/id/eprint/16681

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