Despars, Geneviève et St-Pierre, Yves 
ORCID: https://orcid.org/0000-0002-1948-2041
(2011).
Bidirectional interactions between bone metabolism and hematopoiesis
Experimental Hematology
, vol. 39
, nº 8.
pp. 809-16.
DOI: 10.1016/j.exphem.2011.04.008.
Résumé
Interactions between hematopoiesis and bone metabolism have been described in various developmental and pathological situations. Here we review this evidence from the literature with a focus on microenvironmental regulation of hematopoiesis and bone metabolism. Our hypothesis is that this process occurs by bidirectional signaling between hematopoietic and mesenchymal cells through cell adhesion molecules, membrane-bound growth factors, and secreted matrix proteins. Examples of steady-state hematopoiesis and pathologies are presented and support our view that hematopoietic and mesenchymal cell functions are modulated by specific microenvironments in the bone marrow.
| Type de document: | Article |
|---|---|
| Mots-clés libres: | - |
| Centre: | Centre INRS-Institut Armand Frappier |
| Date de dépôt: | 24 mars 2024 21:45 |
| Dernière modification: | 24 mars 2024 21:45 |
| URI: | https://espace.inrs.ca/id/eprint/14590 |
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