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Nanotechnology for cerebral delivery of nutraceuticals for the treatment of neurodegenerative diseases

Sahni, Jasjeet Kaur; Doggui, Sihem; Dao, Le et Ramassamy, Charles ORCID logoORCID: https://orcid.org/0000-0002-3252-5878 (2011). Nanotechnology for cerebral delivery of nutraceuticals for the treatment of neurodegenerative diseases In: Functional Foods, Nutraceuticals, and Degenerative Disease Prevention. John Wiley & Sons, Danvers, MA, pp. 263-283.

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Résumé


It is estimated that more than 24 million people sufferhave from dementia today and Alzheimer's disease (AD) represents the most common form of dementia. Therefore, there is a critical need to develop new strategies to prevent or to slow down the progression of AD. Recent studies suggested that certain diets, beverages, polyphenols, functional foods and nutraceutical compounds could be associated with a lower incidence of AD. The enhanced bioavailability and/or efficacy associated with the formulation of targeted nanoparticles of various drugs and bioactive agents used in neurodegenerative disorders may provide a possible solution to overcome many of the challenges for the treatment of these diseases. This chapter will focus on the most important materials to produce nanoparticles for cerebral delivery of nutraceutical compounds delivered after an orally administration. Enhanced bioavailability of these compounds in the future will bring them to the forefront of therapeutic agents for the prevention and treatment of AD.

Type de document: Chapitre de livre
Mots-clés libres: -
Centre: Centre INRS-Institut Armand Frappier
Date de dépôt: 01 avr. 2024 01:53
Dernière modification: 01 avr. 2024 01:53
URI: https://espace.inrs.ca/id/eprint/14249

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