Dépôt numérique

Inflammation and neutrophils: A short introduction

Girard, Denis ORCID logoORCID: https://orcid.org/0000-0002-3342-5027 et Tessier, Philippe A (2007). Inflammation and neutrophils: A short introduction In: Phenotypic and functional changes of neutrophils activated by recently identified modulators. Research Signpost, Trivandrum, Kerala, India, pp. 1-8.

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A review. A short introduction regarding the role of polymorphonuclear cell in inflammation is presented. Neutrophils are important cells of the immune system which provide a very useful defense against bacterial and fungal infection. PMN cell turnover must be under strict control to prevent disease, deregulation of the neutrophil apoptotic rate can lead to cancer, autoimmunity or inflammation. The control or delay of basal apoptotic rate of PMNs by an agent would be harmful for the host during inflammation because it could damage the tissue by releasing their toxic products. Thus, it offers a new idea for the development of future potential therapeutic strategies for elimination of apoptotic PMNs during an inflammatory state.

Type de document: Chapitre de livre
Mots-clés libres: Apoptosi; Cell migration; Human; Inflammation; Neutrophil (role of neutrophils in inflammation)
Centre: Centre INRS-Institut Armand Frappier
Date de dépôt: 04 mars 2024 03:17
Dernière modification: 04 mars 2024 03:17
URI: https://espace.inrs.ca/id/eprint/14237

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