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Antimicrobial and Potential Cancer Preventive Substances from Marine Algae and Cyanobacteria Collected in Hawaii and the Caribbean

Lacroix, Monique ORCID logoORCID: https://orcid.org/0000-0002-2042-4033; Dussault, Dominic; Vansach, Tifanie; Vu, Khanh Dang; Horgen, David et Gerhaeuser, Clarissa (2012). Antimicrobial and Potential Cancer Preventive Substances from Marine Algae and Cyanobacteria Collected in Hawaii and the Caribbean In: Phytochemial Society of North America 50th Anniversary Meeting, December 10-15, 2011, Hawaii.

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Résumé


We investigated the effects of a small collection of marine-derived extracts and isolates on the reduction of foodborne illness and prevention of cancer. Ten cyanobacterial isolates and nine organic algal extracts from organisms collected in Caribbean and Hawaiian waters were tested against foodborne pathogens using a broth dilution assay. Results showed that several extracts and compounds showed antimicrobial activity against three Gram positive foodborne pathogens at low concentrations (< 500 ppm). Results also showed that extracts of Gracilaria salicornia, Liagora sp. and Ulva sp. demonstrated high potential to suppress carcinogen metabolic activation through induction of NQO1. This research demonstrates the potential of several cyanobacterial isolates as sources of biologically active substances for the control of foodborne pathogens and for potent inducers of an important enzyme in reducing carcinogen activation.

Type de document: Document issu d'une conférence ou d'un atelier
Informations complémentaires: Affiche scientifique Pharmaceutical Biology 50(5):563-563
Mots-clés libres: -
Centre: Centre INRS-Institut Armand Frappier
Date de dépôt: 28 janv. 2024 15:04
Dernière modification: 28 janv. 2024 15:04
URI: https://espace.inrs.ca/id/eprint/14128

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