Dépôt numérique

Night Work and the Risk of Cancer Among Men

Parent, Marie-Élise ORCID logoORCID: https://orcid.org/0000-0002-4196-3773; El-Zein, Mariam; Rousseau, Marie-Claude ORCID logoORCID: https://orcid.org/0000-0001-5215-8086; Pintos, Javier et Siemiatycki, Jack (2012). Night Work and the Risk of Cancer Among Men American Journal of Epidemiology , vol. 176 , nº 9. pp. 751-759. DOI: 10.1093/aje/kws318.

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Night work might influence cancer risk, possibly via suppression of melatonin release. In a population-based case-control study conducted in Montreal, Quebec, Canada, between 1979 and 1985, job histories, including work hours, were elicited from 3,137 males with incident cancer at one of 11 anatomic sites and from 512 controls. Compared with men who never worked at night, the adjusted odds ratios among men who ever worked at night were 1.76 (95 confidence interval (CI): 1.25, 2.47) for lung cancer, 2.03 (95 CI: 1.43, 2.89) for colon cancer, 1.74 (95 CI: 1.22, 2.49) for bladder cancer, 2.77 (95 CI: 1.96, 3.92) for prostate cancer, 2.09 (95 CI: 1.40, 3.14) for rectal cancer, 2.27 (95 CI: 1.24, 4.15) for pancreatic cancer, and 2.31 (95 CI: 1.48, 3.61) for non-Hodgkins lymphoma. Equivocal evidence or no evidence was observed for cancers of the stomach (odds ratio (OR) 1.34, 95 CI: 0.85, 2.10), kidney (OR 1.42, 95 CI: 0.86, 2.35), and esophagus (OR 1.51, 95 CI: 0.80, 2.84) and for melanoma (OR 1.04, 95 CI: 0.49, 2.22). There was no evidence of increasing risk with increasing duration of night work, with risks generally being increased across all duration categories. Results suggest that night work may increase cancer risk at several sites among men.

Type de document: Article
Mots-clés libres: case-control studies; circadian rhythm; men; neoplasms; night work; occupations; shift work
Centre: Centre INRS-Institut Armand Frappier
Date de dépôt: 09 mars 2024 15:33
Dernière modification: 09 mars 2024 15:33
URI: https://espace.inrs.ca/id/eprint/14072

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