Sallam, Lamyaa M, Shiao, Tze Chieh, Sehad, Celia, Azzouz, Abdelkrim et Roy, René (2019). Accelerated synthesis of surface functionalized mannosylated dendrimers built on cyclotriphosphazene core MRS Advances , vol. 4 , nº 59-60. p. 3187-3198. DOI: 10.1557/adv.2019.375.
Ce document n'est pas hébergé sur EspaceINRS.Résumé
The syntheses of five propargylated dendrimer scaffolds ranging from 2, 3, 4, 6, and 12 surface groups are described together with a 2-azidoethyl α-D-mannopyranoside. The former is appended to the core structure using highly efficient copper-catalysed azide-alkyne cycloaddition (CuAAC) (click reaction) to provide glycodendrimers in an accelerated approach. Two of the core structures are based on cyclotrisphosphazene, thus expanding the scope of the onion-peel strategy to build dendritic architectures with a large number of surface groups at the G1 generation only. © Materials Research Society 2019.
| Type de document: | Article |
|---|---|
| Mots-clés libres: | Biomaterial; Chemical Synthesis; Nanostructure |
| Centre: | Centre INRS-Institut Armand Frappier |
| Date de dépôt: | 30 juin 2022 14:09 |
| Dernière modification: | 30 juin 2022 14:09 |
| URI: | https://espace.inrs.ca/id/eprint/12439 |
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