Dépôt numérique

Inter-rater reliability of occupational exposure assessment in a case-control study of female breast cancer

Batisse, Emmanuelle, Labreche, France, Goldberg, Mark S, Lavoué, Jérome, Parent, Marie-Élise ORCID: https://orcid.org/0000-0002-4196-3773, Pasquet, Romain, Richardson, Lesley, Siemiatycki, Jack et Ho, Vikki (2021). Inter-rater reliability of occupational exposure assessment in a case-control study of female breast cancer Journal of Occupational and Environmental Hygiene , vol. 18 . p. 522-531. DOI: 10.1080/15459624.2021.1976412.

Ce document n'est pas hébergé sur EspaceINRS.


The objective of this paper was to estimate the inter-rater reliability of expert assessments of occupational exposures. An inter-rater reliability sub-study was conducted within a population-based case-control study of postmenopausal breast cancer. Detailed information on lifetime occupational histories was obtained from participants and two industrial hygienists assigned exposures to 185 jobs using a checklist of 293 agents. Experts rated exposure for each job-agent combination according to exposure status (unexposed/exposed), confidence that the exposure occurred (possible/probable/definite), intensity (low/medium/high), and frequency (% time per week). The statistical unit of observation was each job-agent assessment (185 jobs ×293 agents =54,205 assessments per expert). Crude agreement, Gwet AC1/2 statistics and Cohen's Kappa were used to estimate inter-rater agreement for confidence and intensity; for frequency, the intra-class correlation coefficient (ICC) was used. The majority of job-agent combinations were evaluated by the two experts to be not exposed (crude agreement >98% of decisions). The degree of agreement between the experts for the confidence of exposure status was Gwet AC1/2 = 0.99 (95%CI: 0.99-0.99), and for intensity, a Gwet AC2 = 0.99 (95%CI: 0.99-0.99). For frequency, an ICC of 0.31 (95%CI: 0.26-0.35) was found. A sub-analysis restricted to job-agent combinations for which the two experts agreed on exposure status revealed a moderate agreement for confidence of exposure (Gwet AC2 = 0.66) and high agreement for intensity (Gwet AC2 = 0.96). For frequency, the ICC was 0.52 (95% CI: 0.47-0.57). A high level of inter-rater agreement was found for identifying exposures and for coding intensity, but agreement was lower for the coding of frequency of exposure.

Type de document: Article
Mots-clés libres: Epidemiology; Hygiene; Occupational Health; Retrospective Studies; Women
Centre: Centre INRS-Institut Armand Frappier
Date de dépôt: 22 juin 2022 19:11
Dernière modification: 22 juin 2022 19:11
URI: https://espace.inrs.ca/id/eprint/12291

Actions (Identification requise)

Modifier la notice Modifier la notice