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Iron oxide nanoparticles: Question of nanosafety for nanomedicine applications

Saafane, Abdelaziz et Girard, Denis . Iron oxide nanoparticles: Question of nanosafety for nanomedicine applications In: NanoInnovation 2020, 15-18 September 2020, Rome, Italie.

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Résumé

Iron oxide nanoparticles (Fe₃O₄ NPs) are probably the NPs that have received the most increasing attention in nanomedicine. These NPs have been found to possess some properties related with their superparamagnetic behaviour. In fact, this characteristic offers them a great potential to develop a variety of applications in medicine, including the treatment of iron deficiency, thermotherapy, drug delivery and so on. However, many safety concerns are rising, mostly regarding their interactions with innate immune cells. For example, their capacity to induce inflammation, which is one of the most undesired side effects associated with NP exposures, needs to be studied more in depth. The aim of this project is to understand the effects of Fe₃O₄ NPs on the biology of human neutrophils, key player cells in inflammation and the most important leukocyte population present in the circulation.

Type de document: Document issu d'une conférence ou d'un atelier
Informations complémentaires: Affiche scientifique no P.S. 66 présentation vidéo: https://www.nanoinnovation2020.eu/home/poster/Abdelaziz%20saafane%20Presentation.mp4
Mots-clés libres: -
Centre: Centre INRS-Institut Armand Frappier
Date de dépôt: 14 juill. 2021 15:52
Dernière modification: 14 juill. 2021 15:52
URI: https://espace.inrs.ca/id/eprint/11825

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