Dépôt numérique

You are what you eat: preliminary evidence of associations between dietary habits and oral microbiota composition in early childhood

Henderson, Melanie, Nicolau, Belinda, Van Hulst, Andraea, Simoneau, Gabrielle, Barnett, Tracie A, Drapeau, Vicky, Tremblay, Angelo, Mathieu, Marie-Ève, Paradis, Gilles, Zappitelli, Michael, Varin, Thibaut et Marette, André (2019). You are what you eat: preliminary evidence of associations between dietary habits and oral microbiota composition in early childhood In: 58th Annual Meeting of the European Society for Paediatric Endocrinology (ESPE), 19-21 September 2019, Vienna, Austria.

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Background: Oral microbiota composition and diversity differ between obese and non-obese individuals. However, the associations between lifestyle habits (implicated in the pathogenesis of obesity) and the oral microbiota remain uncertain, particularly among children.

Objective: To explore the associations between oral microbiota diversity and lifestyle habits among 8-10 year-old children.

Methods: Data stem from the baseline assessment of the QUALITY cohort, a prospective cohort study of 630 children aged 8-10 years at recruitment, with a parental history of obesity. Lifestyle habits assessed include: physical activity by 7-day accelerometry, self-reported screen time, and dietary intake by 3 non-consecutive 24h dietary recalls. Fitness was measured by VO2peak. 16S-rRNA based microbial profiling of oral plaque samples obtained from 80 participants (40 normal weight, 40 overweight/obese) were performed to determine the diversity of the oral microbiota. Measures of diversity include Observed OTUs, Chao1, Shannon and Simpson reciprocal indices. Pearson's correlations assessed associations between diversity indices and lifestyle habits.

Results: Percent carbohydrate intake was positively correlated with all measures of diversity (Obs OTUs r=0.22, P=0.06; Chao1 r=0.23, P=0.042; Shannon r=0.19, P=0.096; Simpson reciprocal r=0.20, P=0.076). Conversely, while not reaching statistical significance, modest negative correlations between total dietary fat and saturated dietary fat consumption and measures of oral microbiota diversity were noted (r = -0.14 to -0.17 across all indices). Physical activity, fitness and screen time were not associated with oral microbiota diversity at 8-10 yr.

Conclusions: These preliminary findings suggest that dietary intake in childhood is associated with the bacterial diversity of the oral cavity.

Type de document: Document issu d'une conférence ou d'un atelier
Informations complémentaires: affiche scientifique P1-197 Hormone Research in Paediatrics 91(suppl 1):225 https://doi.org/10.1159/000501868
Mots-clés libres: -
Centre: Centre INRS-Institut Armand Frappier
Date de dépôt: 23 juill. 2021 17:13
Dernière modification: 23 juill. 2021 17:13
URI: https://espace.inrs.ca/id/eprint/11725

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