Dépôt numérique

Innate Immune Sensing by Cells of the Adaptive Immune System


Téléchargements par mois depuis la dernière année

Plus de statistiques...

Stogerer, Tanja et Stäger, Simona ORCID logoORCID: https://orcid.org/0000-0001-5508-9565 (2020). Innate Immune Sensing by Cells of the Adaptive Immune System Frontiers in Immunology , vol. 11 , nº 1081. pp. 1-11. DOI: 10.3389/fimmu.2020.01081.

[thumbnail of Innate Immune Sensing by Cells of the Adaptive Immune System-stager 2020.pdf]
PDF - Version publiée
Disponible sous licence Creative Commons Attribution.

Télécharger (2MB) | Prévisualisation


Sensing of microbes or of danger signals has mainly been attributed to myeloid innate immune cells. However, T and B cells also express functional pattern recognition receptors (PRRs). In these cells, PRRs mediate signaling cascades that result in different functions depending on the cell's activation and/or differentiation status, on the environment, and on the ligand/agonist. Some of these functions are beneficial for the host; however, some are detrimental and are exploited by pathogens to establish persistent infections. In this review, we summarize the available literature on innate immune sensing by cells of the adaptive immune system and discuss possible implications for chronic infections.

Type de document: Article
Mots-clés libres: B and T cells; DAMPs; PRRs; TLRs; adaptive immunity; chronic infections
Centre: Centre INRS-Institut Armand Frappier
Date de dépôt: 20 juill. 2021 21:41
Dernière modification: 16 févr. 2022 15:06
URI: https://espace.inrs.ca/id/eprint/11692

Gestion Actions (Identification requise)

Modifier la notice Modifier la notice