Dépôt numérique
RECHERCHER

Radiosensitivity increase in FCV-F9 virus using combined treatments with natural antimicrobials and γ-irradiation

Gobeil, Alexandra, Shankar, Shiv et Lacroix, Monique ORCID: https://orcid.org/0000-0002-2042-4033 (2020). Radiosensitivity increase in FCV-F9 virus using combined treatments with natural antimicrobials and γ-irradiation Journal of Applied Microbiology , vol. 128 , nº 6. p. 1534-1546. DOI: 10.1111/jam.14596.

Ce document n'est pas hébergé sur EspaceINRS.

Résumé

Aims: The objective was to evaluate the possible synergistic effect of cranberry juice (CJ) and commercial citrus extract (BS) against FCV-F9 viral titre in vitro in combination with γ-irradiation and to determinate the D10 values and radiosensitivity increase. Methods and

Results: Virus samples were treated with a formulation containing a mixture of BS or CJ. Results showed a D10 of 0·05, 0·42% and 1·34 kGy for the virus treated with the BS, the CJ and the irradiation alone respectively. Concentrations needed to reduce 6 log TCID50 ml−1 of viral titre were BS-0·3%, CJ-2·52% and 8·04 kGy. Irradiation combined with BS-0·01% and CJ-0·1% against FCV-F9 virus showed D10 values of 0·74 and 0·72 kGy, respectively, resulting in a viral radiosensitization of 1·28 and 1·50 for respective treatments.

Conclusion: The higher viral radiosensitization observed after combining γ-irradiation with BS-0·01% and CJ-0·1% indicates that CJ and BS could be used as antiviral agents alone or in combination with γ-irradiation to prevent NoV outbreaks. Significance and Impact of the Study: Cranberry juice and BS could be used in hurdle approaches in combined treatment with γ-irradiation to assure food safety without a detrimental effect on nutritional value and maintain low processing cost.

Type de document: Article
Mots-clés libres: antimicrobials; food safety; nonthermal processes; postharvest; viruses
Centre: Centre INRS-Institut Armand Frappier
Date de dépôt: 15 juill. 2021 14:43
Dernière modification: 15 févr. 2022 18:40
URI: https://espace.inrs.ca/id/eprint/11588

Actions (Identification requise)

Modifier la notice Modifier la notice