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Certaines bactéries de la flore commensale exacerberaient-elles la carcinogenèse colorectale ?

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Raisch, Jennifer; Dalmasso, Guillaume; Bonnet, Richard; Barnich, Nicolas; Bonnet, Mathilde; Bringer, Marie-Agnès (2016). Certaines bactéries de la flore commensale exacerberaient-elles la carcinogenèse colorectale ? Médecine sciences : M/S , vol. 32 , nº 2. p. 175-82. DOI: 10.1051/medsci/20163202011.

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Résumé

The gut microbiota maintains a relationship with its host with strong mutual benefits. Changes in the composition of the intestinal microbiota have been detected in colorectal cancer patients to the extent that it is now considered as a real contributing factor in this pathology. In this review, we focus on three commensal bacterial species, namely Bacteroides fragilis, Fusobacterium nucleatum, and Escherichia coli, which seem to emerge as pathogens and to contribute to colorectal carcinogenesis through their inflammatory and oncogenic properties.

Type de document: Article
Mots-clés libres: Animals; Bacterial Physiological Phenomena; Bacteroides fragilis/pathogenicity; Carcinogenesis/pathology; Colorectal Neoplasms/ microbiology/ pathology; Disease Progression; Escherichia coli/pathogenicity; Fusobacterium nucleatum/pathogenicity; Gastrointestinal Tract/microbiology/pathology; Humans; Symbiosis/ physiology
Centre: Centre INRS-Institut Armand Frappier
Date de dépôt: 25 févr. 2019 21:05
Dernière modification: 25 févr. 2019 21:05
URI: http://espace.inrs.ca/id/eprint/5574

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